Evidence map›Paper›PMID 40888920›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Safety and efficacy of neuroendoscopic lavage for the management of neonatal intraventricular haemorrhage.

Susan I Honeyman, Alexandros Boukas, Sean C Martin, Tim Lawrence, Amedeo Calisto, Jayaratnam Jayamohan, Shailendra Magdum

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Susan I HoneymanDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. susan.honeyman@ouh.nhs.uk.ORCID http://orcid.org/0000-0002-5117-9405
Alexandros BoukasDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Sean C MartinDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Tim LawrenceDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Amedeo CalistoDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Jayaratnam JayamohanDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Shailendra MagdumDepartment of Paediatric Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal management for neonatal intraventricular haemorrhage (IVH) remains uncertain. Neuroendoscopic lavage (NEL) has gained interest as a method for removal of intraventricular haematoma and debris, with outcomes suggesting it to be safe and efficacious for reducing the requirement for ventriculoperitoneal shunt (VPS) insertion. We present a large series assessing outcomes from NEL for neonatal IVH.

methodsA retrospective review was carried out, between January 2011 and November 2023, identifying infants who underwent NEL following germinal matrix haemorrhage at our institution. Data was extracted on patient baseline demographics, comorbidities, complications, re-operation rate, and VPS requirement.

resultsForty-four patients (28 M:16F) underwent NEL at a median corrected age of 35

conclusionsNEL is a safe and potentially efficacious treatment for neonatal IVH. The procedure may reduce shunt dependence, particularly if performed earlier in the disease process.

Indexed as

Cerebral HemorrhageCerebral Intraventricular HemorrhageNeuroendoscopyTherapeutic IrrigationFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesTreatment OutcomeVentriculoperitoneal ShuntEndoscopic washoutIVHPrematurity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.