Evidence map›Paper›PMID 40888905›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Does screw alignment affect tether breakage in vertebral body tethering?

Sandra Wan, Ogulcan Guldeniz, Chun Hei Christopher Yip, Wanis Nafo, Jason Pui Yin Cheung, Kenny Yat Hong Kwan, Stéfan Parent, Michelle C Welborn, Amer Samdani, Ron El Hawary and 3 more

Abstract readMulticenter Study
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Sandra WanUniversity of Hong Kong, Hong Kong, China. sandrawan@connect.hku.hk.
Ogulcan GuldenizUniversity of Hong Kong, Hong Kong, China.
Chun Hei Christopher YipUniversity of Hong Kong, Hong Kong, China.
Wanis NafoUniversity of Galway, Galway, Ireland.
Jason Pui Yin CheungUniversity of Hong Kong, Hong Kong, China.
Kenny Yat Hong KwanUniversity of Hong Kong, Hong Kong, China.
Stéfan ParentUniversity of Montreal, Montreal, Canada.
Michelle C WelbornShriners Hospitals for Children - Portland, Portland, United States.
Amer SamdaniShriners Hospitals for Children - Philadelphia, Philadelphia, United States.
Ron El HawaryHarvard University, Cambridge, United States.
Michael G VitaleColumbia University, New York, United States.
Kenneth M C CheungUniversity of Hong Kong - Shenzhen Hospital, Shenzhen, China.
Pediatric Spine Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVertebral body tethering (VBT) is a non-fusion surgery for treating idiopathic scoliosis, with tether breakage as a common complication that occurs in 19–52% of patients. It has been reported in mechanical studies that screw malalignment > 1 mm may cause tether breakage. This is a clinical study aiming to assess the effect of screw alignment on tether breakage.

methodsThis was a retrospective multicenter cohort study of 115 patients with idiopathic scoliosis who underwent VBT. Clinical data and radiographic parameters such as Cobb angle, screw malalignment, and inter-screw angle were evaluated postoperatively and at 2-year and 3-year follow-ups. Tether breakage was defined as increase in inter-screw angle ≥ 5°, while screw malalignment was defined as > 25% displacement relative to adjacent screws. Mean screw malalignment was compared between broken and intact tether segments.

resultsMean screw malalignment across all levels was 20.6 ± 17%. Overall, screw malalignment was not found to be significantly associated with tether breakage. For the 36 screws (6%) and 5 screws (0.7%) with moderate and severe malalignment, none were associated with tether breakage. DISCUSSION: In this cohort with satisfactory overall screw alignment, screw malalignment was not found to be associated with tether breakage. Other risk factors that could contribute to tether breakage should be investigated. While excellent screw alignment is unlikely to prevent tether breakage, relative alignment should still be achieved to maintain curve correction and avoid damage to nearby organs.

Indexed as

Bone ScrewsScoliosisVertebral BodyAdolescentChildFemaleHumansMaleRadiographyRetrospective StudiesAdolescent idiopathic scoliosisTether breakageVertebral body tethering

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.