ReviewNaunyn-Schmiedeberg's archives of pharmacology2026
Biosurfactants as next-generation antimicrobials: mechanistic insights and applications in antibiofilm strategies for combatting antimicrobial resistance.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Beyond probiotics: Lacticaseibacillus rhamnosus as a multi-target antagonist of Pseudomonas aeruginosa infections.Folia microbiologica · 2026Review
- The role of microbial biosurfactants in enhancing wound repair: a comprehensive review.Folia microbiologica · 2026Review
- Biosurfactants as Antibiofilm Agents for Medical Devices: Mechanisms, Evidence and Integration into Infection Prevention and Control.Microorganisms · 2026Review
- A Glycolipid-Like Biosurfactant Molecule Derived From anInternational journal of microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Biosurfactants, amphiphilic molecules produced by microorganisms, are emerging as promising next-generation antimicrobials due to their diverse structures and mechanisms of action. This review explores the potential of biosurfactants in combating antimicrobial resistance (AMR) and their applications across various fields. We discuss the classification of biosurfactants, including glycolipids, lipopeptides, and phospholipids, highlighting their unique structural features and microbial origins. Key antimicrobial mechanisms are examined, focusing on membrane disruption, biofilm inhibition, quorum sensing interference, and immunomodulation. We detail the applications of biosurfactants in medicine, including their potential as therapeutic agents against multidrug-resistant pathogens and their use in drug delivery systems to enhance solubility and targeted delivery. Furthermore, we explore their agricultural applications as biocontrol agents and plant growth promoters, emphasizing their environmental compatibility. The review underscores the potential of biosurfactants to address the challenges posed by AMR and highlights future research directions, including genetic engineering, nanotechnology-based delivery, and clinical trials, to fully realize their therapeutic potential.
Indexed as
Identifiers
40888881What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.