Evidence map›Paper›PMID 40888809›Full record

ArticleMultidisciplinary respiratory medicine2025

Performance study of a new diagnostic questionnaire for (Chronic obstructive pulmonary -disease) COPD with information on exposure to wood smoke, COPD-WS.

Alejandra Lozano-Forero, Eduardo Tuta-Quintero, Alirio R Bastidas, Irma Méndez-Aguirre, Miguel A Molina, Julian Camacho, Ivan Guerrero, Laura Ramirez, Maria Perez, Laura Bravo and 8 more

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Article in Multidisciplinary respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

18 authors.

Alejandra Lozano-ForeroDepartment of Epidemiology, Universidad de La Sabana, Chía, Colombia.
Eduardo Tuta-QuinteroDepartment of Internal Medicine, Universidad de La Sabana, Chía, Colombia.
Alirio R BastidasUniversidad de La Sabana, Chía, Colombia.
Irma Méndez-AguirreDepartment of Internal Medicine, Universidad de La Sabana, Chía, Colombia.
Miguel A MolinaSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Julian CamachoSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Ivan GuerreroSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Laura RamirezSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Maria PerezSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Laura BravoSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Silvia RojasSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Juan MejiaSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Paula SalazarSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Daniel MaestreSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Juan MorenoSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Laura CabreraSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Lina BorjasSchool of Medicine, Universidad de La Sabana, Chía, Colombia.
Miguel ChaconSchool of Medicine, Universidad de La Sabana, Chía, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine the diagnostic performance of a new questionnaire (COPD-WS) that considers also exposure to wood smoke for diagnosing Chronic Obstructive Pulmonary Disease (COPD) in a Colombian population.

methodsA cross-sectional study was conducted with analysis of diagnostic tests in subjects with and without COPD. Clinical variables were selected based on their relevance to COPD diagnosis, including age, sex, smoking status, exposure to wood smoke, dyspnea, cough, chronic expectoration, and wheezing. A bivariate analysis was performed with the diagnosis of COPD by spirometric criteria. The area under the receiver operating characteristic curve (AUROC) was calculated for the new questionnaire and compared with the LFQ, CDQ, PUMA, COULD IT BE COPD, and COPD-PS questionnaires. The cutoff point for the new questionnaire was obtained through the Youden index, and a p-value <0.05 was considered statistically significant.

resultsA total of 681 patients were included, 187 (27.5%) diagnosed with COPD. The mean age of the population was 65.9 (SD: ±11.79) years, with 53.7% being women and 58.3% having been exposed to wood smoke. The variables included in the questionnaire were age, sex, smoking status, exposure to wood smoke, dyspnea, cough, chronic expectoration, and wheezing. The AUROC for the new COPD-WS questionnaire was 0.69 (95%CI:0.65-0.74;p<0.001), and for a cutoff point ≥6, sensitivity was 0.711 (95%CI:0.677-0.745), specificity was 0.575 (95%CI:0.538-0.612), PPV was 0.388 (95% CI:0.351-0.424), NPV was 0.840 (95%CI:0.813-0.868), LR+ was 1.673 (95%CI:1.458-1.919), LR- was 0.502 (95% CI:0.438-0.576).

conclusionThis new questionnaire COPD-WS demonstrates acceptable diagnostic capability for diagnosis of COPD in this symptomatic population, and its performance is comparable to other questionnaires currently in use.

Identifiers

PMID40888809
PMCPMC12459959

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