ReviewRegenerative medicine2025
Optimizing methods for regenerative endodontics.
Review in Regenerative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Regenerative endodontics: current concepts, clinical challenges, and emerging therapies.Brazilian oral research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Regenerative endodontics has emerged as a promising and recognized approach for treating necrotic young permanent teeth. Based on advanced tissue engineering strategies, regenerative therapies, such as cell homing and cell-based transplantation, have been extensively investigated to achieve functional regeneration of the injured pulp-dentin complex. Injectable, thermo-responsive, and tailor-made 3D-printed scaffolds that carry antimicrobial, anti-inflammatory, and other signaling cues provide a powerful means of delivering drugs precisely within the narrow, branching anatomy of the root canal. By enhancing antimicrobial decontamination, an essential step in the regenerative process, these biomaterials establish a permissive microenvironment that promotes cellular migration, adhesion, and subsequent differentiation. Therefore, the current narrative review emphasizes emerging strategies and their optimization to enhance regenerative outcomes in immature teeth affected by pulp necrosis and apical periodontitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.