Evidence map›Paper›PMID 40888654›Full record

ArticleJournal of global health2025

Associations between season of conception and maternal and perinatal health: a prospective birth cohort study.

Qingxiu Li, Yecheng Miao, Jiayi Chen, Qian Zhang, Bin Sun, Zhengqin Wu, Junwei Liu, Huimin Shi, Haiyan Gao, Wei Li and 3 more

Abstract read
In one paragraph

Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Qingxiu Li *Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Yecheng Miao *School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Jiayi ChenFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Qian ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China.
Bin SunFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Zhengqin WuFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Junwei LiuFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Huimin ShiFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Haiyan GaoFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Wei LiFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Wenjuan LiuFujian Children's Hospital, Fuzhou, China.
Yibing ZhuFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Haibo LiFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Global maternal health progress stagnated during the Sustainable Development Goal era, while the impact of meteorological conditions on maternal-infant outcomes remains contentious. We aimed to investigate the relationship between the season of conception and adverse perinatal outcomes. Methods: We conducted a prospective cohort study, collecting basic demographic characteristics of pregnant women and estimating the season of conception based on the date of the last menstrual period. We did a follow-up until delivery to monitor pregnancy health issues, such as gestational diabetes mellitus (GDM), gestational hypertension (GH), premature rupture of membranes (PROM), and postpartum haemorrhage (PPH), as well as neonatal health indicators such as birth weight and other relevant outcomes. Results: We included data from 26 341 pregnant women in our analysis. The average age of pregnant women was 30.3 years (standard deviation (SD) = 4.0), and 60.9% were primiparas. Compared to conception in spring (reference group), conception in summer was associated with a 15% reduction in GDM risk (odds ratio (OR) = 0.85; 95% confidence interval (CI) = 0.77-0.94) and a 10% lower PROM risk (OR = 0.90; 95% CI = 0.82-0.99), but a 46% increased PPH risk (OR = 1.46; 95% CI = 1.07-1.99). Conceptions in autumn and winter demonstrated even more pronounced protective effects, with the former showing a GDM risk reduction of 23% (OR = 0.77; 95% CI = 0.70-0.85) and 26% lower GH risk (OR = 0.74; 95% CI = 0.61-0.90), and the latter a 14% GDM risk reduction (OR = 0.86; 95% CI = 0.79-0.94) and 20% lower GH risk (OR = 0.80; 95% CI = 0.68-0.96). Conclusions: We found that conception in spring was associated with an increased risk of GDM, GH, and PROM, while conception in summer was linked to a higher risk of PPH. However, the preliminary nature of our findings suggests that further research is needed to confirm causality and assess the feasibility of any potential interventions.

Indexed as

FertilizationMaternal HealthPregnancy ComplicationsSeasonsAdultBirth CohortFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeProspective StudiesYoung Adult

Identifiers

PMID40888654
PMCPMC12400889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.