Trial reportThe journal of vascular access2026
Clinical benefit of adding cyanoacrylate glue during PICC line insertion compared to standard procedure in outpatient cancer patients: Results from the randomized prospective trial PICCandGLUE.
Trial report in The journal of vascular access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeripherally inserted central catheters (PICCs) can be used to administer a variety of intravenous therapies to cancer patients. PICC insertion can be associated with bleeding at the puncture site requiring additional care and dressing repairs. Several studies suggest that the addition of cyanoacrylate glue (CAG) at PICC insertion reduces the risk of bleeding and the further need for compresses, as well as catheter-related complications.
methodsThis monocenter, randomized, controlled, prospective study was conducted in the vascular access unit (VAU) of the French comprehensive cancer center Léon Bérard. The primary objective was to compare the efficacy of PICC insertion with CAG versus without glue in cancer patients requiring central venous access. Success was defined as the absence of compress requirement at the end of the procedure. Secondary objectives included the number of patients needing a change of dressing within 1 h, at day 8 and at day 30, and the incidence of PICC removal and PICC-related complications in the 30 days following insertion.
resultsFrom August 2023 to July 2024, 98 outpatients were randomized (1:1) in the experimental arm (CAG,
conclusionCAG provides an immediate benefit at the end of PICC insertion that lasts for up to 1 h after the end of the procedure. The use of CAG would improve the organization of the catheter placement unit and reduce the need for post-procedure nursing care.
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