ArticleAngewandte Chemie (International ed. in English)2025
Discrete Actuation of Water-Responsive Crystalline Metal-Peptide Frameworks.
Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Discrete Actuation of Water-Responsive Crystalline Metal-Peptide Frameworks.Angewandte Chemie (International ed. in English) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Engineering guest-responsive materials capable of controlled and precise sorption behavior and structural deformation in response to external stimuli is imperative for various applications. However, existing systems often exhibit complex, unpredictable dynamics, posing challenges for efficient control and utilization. Here, we design crystalline metal-peptide frameworks with tunable water-responsive (WR) dynamics by assembling glycine-threonine (Gly-Thr, GT) or glycine-serine (Gly-Ser, GS) peptides with zinc (Zn) ions, achieving either continuous or discrete threshold water-sorption-dependent phase transitions. As ambient relative humidity (RH) changes, the Zn-GT crystal continuously adsorbs or desorbs water, resulting in gradual structural adaptations, similar to those observed in other supramolecular systems. In contrast, the Zn-GS crystal undergoes stepwise water sorption and structural transitions at specific RH thresholds. These contrasting WR modes arise from differences in water binding and structural dynamics; in Zn-GT, each coordinating water molecule contributes varying degrees of framework integrity and evaporates sequentially, whereas in Zn-GS, water molecules with comparable interactions within a flexible framework are released simultaneously during dehydration. Our study demonstrates the mechanism by which host-guest interactions can be harnessed to control dynamic sorption and actuation behavior of supramolecular materials at the molecular level, offering mechanistic insights that may guide the rational design of next-generation programmable, stimulus-responsive systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.