Evidence map›Paper›PMID 40888083›Full record

ArticleVeterinary dermatology2026

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo.

Adamantia Pseftogka, Elisabeta Samuel Badulescu, Manolis K Chatzis, Manolis N Saridomichelakis

Abstract read
In one paragraph

Article in Veterinary dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adamantia PseftogkaClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID https://orcid.org/0009-0000-1871-0594
Elisabeta Samuel BadulescuClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID https://orcid.org/0000-0002-4478-3591
Manolis K ChatzisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID https://orcid.org/0000-0001-8451-3708
Manolis N SaridomichelakisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID https://orcid.org/0000-0001-8308-3371

Funding

MP Labo, Grasse, France
6 · The paper itself

Abstract

backgroundNormal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and is aggravated by topical antiseptics. HYPOTHESIS AND

objectivesTo evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs with a chlorhexidine 2%/miconazole 2% product. ANIMALS: Twelve clinically healthy, privately owned dogs. MATERIALS AND

methodsDogs were clipped on the top of the head (control site), right and left lateral thorax. They were bathed on the body trunk with the chlorhexidine 2%/miconazole 2% shampoo and subsequently sprayed with Sensiderm on their randomly selected right or left side of the thorax. Skin hydration was measured by electrical capacitance using a corneometer on the three sites before (time point [T]0), and 1-2 h (T1), 6 h (T2), 24 h (T3), 48 h (T4) and 72 h (T5) after interventions.

resultsTwo-way repeated-measures ANOVA showed a significant effect of time (p = 0.015) and a significant time-treatment interaction (p = 0.023) on skin hydration. One-way repeated-measures ANOVA showed that the effect of time was significant only on the Sensiderm spray-treated site, where skin hydration increased over baseline at T1 (p = 0.009; 95% confidence interval [CI] = 3.158-17.231), peaked at T2 (p ≤ 0.014 and 95% CI ≥ 1.680 compared with T0, T3, T4 and T5) and remained increased at T3 (p ≤ 0.037 and 95% CI ≥ 0.482 compared with T0 and T5). No treatment-related adverse effects were seen. CONCLUSIONS AND CLINICAL RELEVANCE: Sensiderm spray was safe, and it increased hydration of healthy canine skin for ≥ 24 h.

Indexed as

Anti-Infective Agents, LocalChlorhexidineMiconazoleSkinAnimalsBathsDogsFemaleMaleAnti-Infective Agents, LocalChlorhexidineMiconazolecorneometryelectrical capacitanceemollientSensiderm sprayskin hydration

Identifiers

PMID40888083
PMCPMC12796995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.