Evidence map›Paper›PMID 40888062›Full record

ArticleAngewandte Chemie (International ed. in English)2025

The Origin of the Feedstock Molecules for Life on the Hadean Earth.

Nikolai Diukarev, Erik Boinowitz, Jonas Feldmann, Stefan Wiedemann, Aleksandr Mikheev, Sidney Becker, Thomas Carell

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Origin of the Feedstock Molecules for Life on the Hadean Earth.Angewandte Chemie (International ed. in English) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nikolai Diukarev *Department of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0009-0005-2432-9841
Erik Boinowitz *Department of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0009-0000-4066-2525
Jonas Feldmann *Department of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0000-0002-3887-2213
Stefan WiedemannDepartment of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0000-0002-6415-4979
Aleksandr MikheevDepartment of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0009-0008-2656-6893
Sidney BeckerDepartment of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0000-0002-4746-2822
Thomas CarellDepartment of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Würmtalstraße 201, 81375, Munich, Germany.ORCID https://orcid.org/0000-0001-7898-2831

Funding

Deutsche Forschungsgemeinschaft 325871075,A04Deutsche Forschungsgemeinschaft 326039064Deutsche Forschungsgemeinschaft 369799452,A27Deutsche Forschungsgemeinschaft 393547839,P2Friedrich Naumann FoundationHorizon 2020 741912(EpiR)RNAmed, Elitenetzwerk BayernVolkswagen Foundation EvoRib
6 · The paper itself

Abstract

The origin of life in the Hadean eon required the formation of amino acids and nucleosides among the key molecules of life. It is assumed that highly unsaturated carbon and nitrogen containing feedstock molecules, which form in a strongly reducing H

Indexed as

Amino acidsNucleosidesOrigin of lifeOximePrebiotic chemistry

Identifiers

PMID40888062
PMCPMC12518691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.