Evidence map›Paper›PMID 40887928›Full record

SynthesisComprehensive reviews in food science and food safety2025

Risk Assessment of Toxic and Potentially Toxic Metals in Raw Goat Milk: A Systematic Review of Global Data and Environmental Factors.

Arlen Carvalho de Oliveira Almeida, Paloma Almeida Rodrigues, Marion Pereira da Costa, Carlos Adam Conte-Junior

Abstract readSystematic Review
In one paragraph

Synthesis in Comprehensive reviews in food science and food safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arlen Carvalho de Oliveira AlmeidaCenter for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil.
Paloma Almeida RodriguesCenter for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil.
Marion Pereira da CostaLaboratory of Technology and Inspection of Milk and Derivatives (LaITLácteos), School of Veterinary Medicine, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.ORCID 0000-0002-3003-6763
Carlos Adam Conte-JuniorCenter for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-6133-5080

Funding

Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
6 · The paper itself

Abstract

Goat milk is a culturally and nutritionally significant food worldwide, yet its safety regarding toxic and trace elements remains poorly defined. The absence of geographically balanced surveillance and the variability in contamination across rural, urban, and industrial environments limit reliable risk assessment for human exposure. We hypothesized that raw goat milk acts as a sentinel matrix for chronic exposure to toxic and potentially toxic elements, with risks strongly influenced by production systems and environmental contexts. Accordingly, the objective of this review was to systematically synthesize evidence from 20 studies conducted across Asia, Europe, and North Africa, quantifying toxic metals (arsenic, lead, cadmium, and mercury) and essential elements (chromium, nickel, copper, zinc, iron, manganese, and aluminum) relative to thresholds established by the World Health Organization (WHO), the European Food Safety Authority (EFSA), and the Institute of Medicine (IOM). Results revealed pronounced heterogeneity, with lead reaching 0.382 ± 0.0026 mg/L in rural Algeria, chromium peaking at 16.423 ± 0.349 mg/L in industrial Asaluyeh and 14.211 ± 0.205 mg/L in rural Kaki, Iran, and pediatric estimated daily intakes (EDIs) for Cr up to 2.74 × 10

Indexed as

Food ContaminationMetals, HeavyMilkAnimalsGoatsHumansRisk AssessmentMetals, Heavybioaccumulationcaprinedairy productsenvironmental contaminationenvironmental factorsfood safetyheavy metalssystematic review

Identifiers

PMID40887928
PMCPMC12399917

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.