Evidence map›Paper›PMID 40887869›Full record

ArticlePharmacology research & perspectives2025

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra-Long-Acting β

Richard G W Proudman, Jillian G Baker

Abstract readComparative Study
In one paragraph

Article in Pharmacology research & perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Novel fenoterol derivatives as suppressors of ERK1/2 phosphorylation in melanoma.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  2. Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Richard G W ProudmanCell Signalling, COMPARE, School of Life Sciences, C Floor Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Jillian G BakerCell Signalling, COMPARE, School of Life Sciences, C Floor Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0003-2371-8202

Funding

Wellcome Trust 073377/Z/03/Z
6 · The paper itself

Abstract

β-agonists have been used in asthma for 120 years. There are two recent changes: ultra-long-acting agonists for COPD and new asthma guidelines recommending formoterol/ICS inhalers phasing out short-acting salbutamol inhalers. Few studies directly compare the molecular pharmacological properties of short (salbutamol, terbutaline, fenoterol), long (formoterol, salmeterol), and ultra-long-acting (indacaterol, olodaterol, vilanterol) β

Indexed as

Adrenergic beta-2 Receptor AgonistsAsthmaBronchodilator AgentsPulmonary Disease, Chronic ObstructiveAnimalsBenzoxazinesBenzyl AlcoholsChlorobenzenesCHO CellsCricetulusFormoterol FumarateHumansIndansQuinolonesReceptors, Adrenergic, beta-2Salmeterol XinafoateAdrenergic beta-2 Receptor AgonistsBenzoxazinesBenzyl AlcoholsBronchodilator AgentsChlorobenzenesFormoterol FumarateindacaterolIndansolodaterolQuinolonesReceptors, Adrenergic, beta-2Salmeterol Xinafoatevilanterol

Identifiers

PMID40887869
PMCPMC12399788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.