Evidence map›Paper›PMID 40887639›Full record

ArticleCritical care (London, England)2025

Pharmacokinetic/Pharmacodynamic of ceftolozane/tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (ECMO): a retrospective cohort analysis.

Alexandre Coppens, Melchior Gautier, Noël Zahr, Helga Junot, Brigitte Rached, David Levy, Ouriel Saura, Juliette Chommeloux, Guillaume Hekimian, Matthieu Schmidt and 3 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexandre CoppensService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Melchior GautierService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Noël ZahrDepartment of Pharmacology, Pharmacokinetics and Therapeutic Drug Monitoring Unit, AP-HP. Sorbonne Université, Pitié-Salpêtrière Hospital, UMR-S 1166, Paris, CIC-1901, F-75013, France.
Helga JunotService de pharmacie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Sorbonne-Université, Paris, France.
Brigitte RachedDMU BioGem, APHP.Sorbonne Université, Bactériologie-Hygiène, Hôpital Pitié-Salpêtrière, CIMI-Paris, Inserm U1135, Sorbonne- Université, Paris, F-75013, France.
David LevyService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Ouriel SauraService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Juliette ChommelouxService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Guillaume HekimianService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Matthieu SchmidtService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Alain CombesService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France.
Alexandre BleibtreuService des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitié- Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne-Université, Hôpital Pitié-Salpêtrière, INSERM U1135 EDIRA CIMI Sorbonne University, Paris, France.
Charles-Edouard LuytService de Médecine Intensive Réanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, Paris Cedex 13, 75651, France. charles-edouard.luyt@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ceftolozane/tazobactamECMOPharmacokinetic

Identifiers

PMID40887639
PMCPMC12400648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.