Evidence map›Paper›PMID 40887634›Full record

ArticleBMC chemistry2025

Validation of a green and sensitive spectrofluorimetric method for determination of Bilastine and its application to pharmaceutical preparations, content uniformity test, and spiked human plasma.

Ahmed S Ahmed, Khalid M Badr El-Din, Ahmed A Khorshed, Sayed M Derayea, Mohamed Oraby

Abstract read
In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed S AhmedDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt. Ahmed.saad@pharm.sohag.edu.eg.
Khalid M Badr El-DinDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.
Ahmed A KhorshedDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
Sayed M DerayeaDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.
Mohamed OrabyDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bilastine (BIL) is a new second-generation antihistaminic drug used for the management of urticaria and rhino-conjunctivitis symptoms. Herein, a spectrofluorimetric method for determining BIL is described. The method is very sensitive, simple, quick, and green. The suggested method depended on the measurement of the original fluorescence of BIL in 1.0 M sulfuric acid at an emission wavelength of 385 nm after an excitation at 272 nm. The method was evaluated by the International Council on Harmonization (ICH) requirements. The relationship between BIL concentrations and the fluorescence intensities was linear in a range of 10.0-500.0 ng mL

Indexed as

BilastineContent uniformityPharmaceutical formulationSpectrofluorimetry

Identifiers

PMID40887634
PMCPMC12400534

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.