Evidence map›Paper›PMID 40887586›Full record

ArticleBMC oral health2025

Patterns and predictors of tooth extraction-related anxiety at sequential perioperative stages.

Zewei Zhang, Yu Zhang, Huan Liu, Feng He, Guowei Li, Yuan Li, Shuyin Zhang, Jingzhen Mo, Hongzhi Zhou, Chen Li and 1 more

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zewei Zhang *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Yu Zhang *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Huan LiuDepartment of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Feng HeState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Guowei LiState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Yuan LiState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Shuyin ZhangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Jingzhen MoState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Hongzhi ZhouState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China.
Chen LiDepartment of Health Statistics, School of Preventive Medicine, the Fourth Military Medical University, Xi'an, China. lcbiosta@fmmu.edu.cn.
Yang XueState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, the Fourth Military Medical University, Xi'an, China. xueyangfmmu@163.com.

Funding

The Fourth Military Medical University 2022LC2236
6 · The paper itself

Abstract

objectiveTo determine the characteristics of anxiety at five different points during tooth extraction, explore the relationship between anxiety and pain, and identify predictors of overall anxiety.

methodsA cross-sectional study was conducted among 302 patients undergoing tooth extraction. Anxiety levels were evaluated using a modified dental anxiety scale (MDAS) at five time points: pre-extraction night (T1), hospital waiting period (T2), local anesthesia administration (T3), extraction procedure (T4), and post-extraction (T5). Repeated-measures ANOVA, one-way ANOVA and Pearson correlation analysis were employed to evaluate temporal variations in anxiety levels and their associations with baseline characteristics and pain perception at each assessment point; Chi-square tests and binary logistic regression modeling were used to identify significant predictors of overall anxiety levels.

resultsThe cohort (mean age 31.3 ± 11.4 years; 60.3% female) demonstrated distinct anxiety patterns throughout the extraction process. Anxiety levels peaked during T3 and T4, followed by a significant post-operative reduction (T5; p < 0.05). Pain (69.5%) and bleeding (67.9%) emerged as the most frequently reported anxiety-inducing factors. Analysis of the correlation between baseline characteristics and anxiety at each time point revealed that younger patients (16-30 years) had smaller anxiety increases during procedures vs. older groups (p = 0.01). Married individuals showed earlier anxiety reduction than unmarried (p = 0.01). Mandibular/bimaxillary extractions and longer durations (> 10 min) correlated with higher intraoperative anxiety (p < 0.05). On the other hand, predicted pain intensity strongly correlated with anxiety at T1-T4 (p < 0.01), while actual pain linked to T4-T5 anxiety (p < 0.01). Postoperative pain showed the strongest association with T5 anxiety (p < 0.001). Risk factor analysis based on overall anxiety levels found that females (OR = 1.76), unemployed individuals (OR = 3.81), and mandibular/bimaxillary extractions (OR = 2.11-2.70) were independent predictors of high overall anxiety. Finally, a prediction model was established. Based on this model, a female unemployed patient with a mandibular third molar had an estimated 72% probability of experiencing anxiety.

conclusionsDental anxiety peaks during invasive procedural phases and is influenced by demographic, clinical, and pain anticipation. The identified risk factors (female, unemployment, mandibular procedures) highlight targets for preoperative interventions. Addressing pain expectations and optimizing patient communication may mitigate anxiety, particularly in high-risk groups. CLINICAL RELEVANCE: This study reveals the anxiety characteristics during the perioperative period of tooth extraction. These insights offer essential evidence for clinicians to identify and address anxiety, ultimately enhancing patient care. Additionally, these findings highlight the importance of effective pain control in developing anxiety management strategies in clinical practice.

trial registrationthe registration number is ChiCTR2400086891, dated July 15, 2024.

Indexed as

Dental AnxietyTooth ExtractionAdolescentAdultAge FactorsCross-Sectional StudiesFemaleHumansMaleMiddle AgedPostoperative PainYoung AdultAnxietyAnxiety prediction modelPainPerioperative periodRisk factorsTooth extraction

Identifiers

PMID40887586
PMCPMC12398968

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.