Evidence map›Paper›PMID 40887538›Full record

ArticleAMB Express2025

Synbiotic microencapsulation of Lactiplantibacillus plantarum-lentinan for enhanced growth in broilers.

Liyang Guo, Lixia Yang, Kun Wang, Weiqi Liu, Shun Wang, Yongjie Zhang, Rui Li, Zhiyong Wu, Chunli Chen

Abstract read
In one paragraph

Article in AMB Express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liyang Guo *College of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Lixia Yang *College of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Kun WangCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Weiqi LiuCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Shun WangCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Yongjie ZhangCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Rui LiCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China.
Zhiyong WuCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China. wuzhiyong@neau.edu.cn.
Chunli ChenCollege of Veterinary Medicine, Northeast Agricultural University, No.600, Changjiang Road, XiangFang District, Harbin, 150030, Heilongjiang Province, People's Republic of China. chunli.chen@neau.edu.cn.

Funding

the International Postdoctoral Exchange Fellowship Program from the Office of China Postdoctoral Council No. 2020106 and PC2020013the National Natural Science Foundation of Heilongjiang Province No. YQ2022C017the Postdoctoral Foundation of Heilongjiang Province LBH-Z19006
6 · The paper itself

Abstract

In the prevention and control of animal diseases, synbiotics combine the principles of probiotics and prebiotics, which play crucial roles in reducing intestinal disorders, such as diarrhea and indigestion, enhancing immune function, and decreasing the incidence of respiratory diseases in livestock and poultry. Following the confirmation of the prebiotic activity of lentinan, this study aimed to use microencapsulation technology to prepare synbiotics composed of Lactiplantibacillus plantarum (L. plantarum) and lentinan. The optimal preparation process for the synbiotic microcapsules was determined through single-factor, orthogonal, and response surface experiments. Subsequent experiments on storage stability, gastric acid tolerance, and intestinal release characteristics confirmed that the microencapsulated L. plantarum-lentinan synbiotic exhibited increased resistance to adverse environments. The microencapsulated synbiotic was ultimately incorporated into antibiotic-free feed at a dosage of 1 × 109 CFU/kg for broilers. The results indicated that this synbiotic could increase the average daily weight gain and feed conversion ratio of 28-day-old broiler chickens, increase the immune organ index, improve the morphology of the intestinal villi, and effectively increase the activity of digestive enzymes in the small intestine. Moreover, changes in the cecal microbial community composition of broilers were observed, with an increase in the number of Lactobacillus and a decrease in the number of Escherichia coli. In summary, this synbiotic can effectively enhance the growth performance of broilers, regulate the intestinal microbiota, improve immune function, and reduce the risk of intestinal and respiratory diseases in broilers.

Indexed as

Broiler growthLactiplantibacillus plantarumLentinanMicroencapsulatedSynbiotics

Identifiers

PMID40887538
PMCPMC12399502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.