ArticleBMJ open2025
Utilisation of artificial intelligence to enhance the detection rates of renal cancer on cross-sectional imaging: protocol for a systematic review and meta-analysis.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe incidence of renal cell carcinoma has steadily been on the increase due to the increased use of imaging to identify incidental masses. Although survival has also improved because of early detection, overdiagnosis and overtreatment of benign renal masses are associated with significant morbidity, as patients with a suspected renal malignancy on imaging undergo invasive and risky procedures for a definitive diagnosis. Therefore, accurately characterising a renal mass as benign or malignant on imaging is paramount to improving patient outcomes. Artificial intelligence (AI) poses an exciting solution to the problem, augmenting traditional radiological diagnosis to increase detection accuracy. This report aims to investigate and summarise the current evidence about the diagnostic accuracy of AI in characterising renal masses on imaging. METHODS AND ANALYSIS: This will involve systematically searching PubMed, MEDLINE, Embase, Web of Science, Scopus and Cochrane databases. Publications of research that have evaluated the use of automated AI, fully or to some extent, in cross-sectional imaging for diagnosing or characterising malignant renal tumours will be included if published between July 2016 and June 2025 and in English. The protocol adheres to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 checklist. The Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) score will be used to evaluate the quality and risk of bias across included studies. Furthermore, in line with Checklist for Artificial Intelligence in Medical Imaging recommendations, studies will be evaluated for including the minimum necessary information on AI research reporting. ETHICS AND DISSEMINATION: Ethical clearance will not be necessary for conducting this systematic review, and results will be disseminated through peer-reviewed publications and presentations at both national and international conferences. PROSPERO REGISTRATION NUMBER: CRD42024529929.
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Registered trials
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