ArticleThe Journal of pediatrics2026
A Qualitative Exploration of Adherence to Methotrexate in Juvenile Idiopathic Arthritis.
Article in The Journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- [Mental health-An underestimated problem? : Psychological burden in transitional care: recommendations for rheumatological practice].Zeitschrift fur Rheumatologie · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveTo identify barriers and facilitators of adherence to methotrexate (MTX) in juvenile idiopathic arthritis (JIA). STUDY
designWe conducted a qualitative cross-sectional study employing semistructured interviews of 20 adolescents with JIA with varying levels of MTX adherence, determined by pharmacy dispense data. We used grounded theory to identify common themes, which we organized into barriers and facilitators, subdivided into World Health Organization adherence domains.
resultsThe sample had equal representation of adherent and nonadherent patients, and of those prescribed oral and injectable MTX. The most common barriers were patient- or medication-related, including anticipatory nausea, anxiety, busy schedules, side effects, and the color, taste, and odor of MTX. Common facilitators included patient-related (reminders, routines, calming techniques, family, autonomy, time since diagnosis) and medication-related factors (autoinjectors, folic acid), as well as some health care system-related (positive clinic experiences), and socioeconomic factors (community medical knowledge).
conclusionsThrough interviews with adolescents on MTX for JIA and using the World Health Organization's framework, we gained valuable insight on the most salient barriers and facilitators of MTX adherence. These findings can inform interventions to improve medication adherence and optimize patients' quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.