Evidence map›Paper›PMID 40886599›Full record

ArticleEcotoxicology and environmental safety2025

Ambient air pollution during developmental windows of spermatogenesis and semen quality among an infertility treatment seeking population.

Lindsey M Russo, J Richard Pilsner, Timothy P Canty, Neil J Perkins, Pauline Mendola, Karen Schliep, May Shaaban, Rachael B Hemmert, Akanksha Singh, Allison M Ring and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecotoxicology and environmental safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lindsey M RussoDivision of General Internal Medicine, Weill Cornell Medicine, 420 East 70th Street, New York, NY 10021, USA.
J Richard PilsnerDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Timothy P CantyDepartment of Atmospheric and Oceanic Science, University of Maryland, College Park, MD 20742, USA.
Neil J PerkinsBiostatistics and Bioinformatics Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Pauline MendolaEpidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA.
Karen SchliepDivision of Public Health, Department of Family and Preventive Medicine, University of Utah Health, Salt Lake, UT, USA.
May ShaabanDivision of Public Health, Department of Family and Preventive Medicine, University of Utah Health, Salt Lake, UT, USA.
Rachael B HemmertDivision of Public Health, Department of Family and Preventive Medicine, University of Utah Health, Salt Lake, UT, USA.
Akanksha SinghDepartment of Atmospheric and Oceanic Science, University of Maryland, College Park, MD 20742, USA.
Allison M RingDepartment of Atmospheric and Oceanic Science, University of Maryland, College Park, MD 20742, USA.
C Matthew PetersonDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake, UT, USA.
Kaniz RabeyaDepartment of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA.
Enrique F SchistermanDepartments of Biostatistics, Epidemiology and Informatics and Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Sunni L MumfordDepartments of Biostatistics, Epidemiology and Informatics and Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Carrie NoblesDepartment of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA. Electronic address: cnobles@umass.edu.

Funding

Exposure to Ambient Air Pollution and Temperature During Spermatogenesis: Impact on Men's Reproductive Health and Infertility Treatment OutcomesK01ES034005 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI NOBLES, CARRIE · 2022 to 2024
$438k
NICHD NIH HHS HHSN275201200007CNICHD NIH HHS HHSN275201300026INIEHS NIH HHS K01 ES034005
6 · The paper itself

Abstract

Prior studies have observed impacts of air pollution on semen quality, but timing of exposure during developmental windows of spermatogenesis and impacts of low-to-moderate air pollution is less well understood. We examined the relation between air pollution and semen quality in the Folic Acid and Zinc Supplementation Trial (2013-2018), which enrolled male partners of couples seeking infertility treatment in the Salt Lake City, Utah region (n = 2015). Semen quality parameters were assessed at baseline, 2-, 4-, and 6-months follow-up. Measures of daily air pollutants at each participant's residence were abstracted from Community Multiscale Air Quality models (fine particulate matter: PM

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureSpermatogenesisAdultHumansInfertility, MaleMaleOzoneParticulate MatterSemen AnalysisUtahAir PollutantsOzoneParticulate MatterAir pollutionEnvironmentInfertility treatmentSemen qualitySpermatogenesisSubfertility

Identifiers

PMID40886599
PMCPMC12413662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.