ReviewAdvances in experimental medicine and biology2025
Circular RNAs in Immune-Related Diseases.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CircRNAs are a novel class of noncoding RNAs characterized by a covalently closed loop structure lacking both a 3' polyadenylation tail and a 5' cap. Increasing evidence demonstrated that circRNAs can participate in several biological processes including immune system physiology and immune-related diseases. CircRNAs act on immune pathways through several molecular mechanisms including miRNAs and RBP sponges, protein scaffolds, and mRNA stability modulation via diverse signaling pathways including MAPK, JAK-STAT, and Wnt signaling pathway. Recently, circRNAs have also been studied as biomarkers for immune diseases as well as new potential therapeutic targets. Effects of dysregulated circRNA levels correlate, among others, with alterations in immune cell behavior, cytokines production, and immune response in general.In this chapter, we describe new experimental progress in circRNAs that participates in the regulation of the immune system and in the pathogenesis of autoimmune diseases and infectious diseases.
Indexed as
Identifiers
40886289What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.