GuidelineHepatology international2025
Management of acute variceal bleeding: updated APASL guidelines.
Guideline in Hepatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Spectral CT predicts initial bleeding risk in cirrhotic patients with esophagogastric varices.Abdominal radiology (New York) · 2026Article
- Successful Endoscopic Sealing of Gastric Perforation With Tissue Adhesive Following Endoscopic Treatment for Gastric Fundal Variceal Bleeding: A Case Report.Clinical case reports · 2026Article
- [Emphasizing the precise application of emergency endoscopy in the treatment of portal hypertensive bleeding in cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- [Medical treatment of portal hypertensive bleeding in cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- Off-Hours Endoscopic Management and Clinical Outcomes in Acute Esophageal Variceal Bleeding: A Real-World Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Extracellular volume fraction derived from spectral CT for liver function reserve evaluation and complication prediction in clinically stable liver cirrhosis.BMC medical imaging · 2026Article
- Predictive performance of CT-based artificial intelligence for predicting variceal bleeding in portal hypertension: a systematic review and meta-analysis.Abdominal radiology (New York) · 2026Review
- Acute-on-chronic liver failure: pathophysiological mechanisms and clinical management.Nature reviews. Gastroenterology & hepatology · 2026Review
- Factors Associated with Early Rebleeding After Endoscopic Variceal Ligation in Cirrhotic Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- When Atrial Fibrillation Meets Alcoholic Liver Cirrhosis: Can Direct Oral Anticoagulants Bridge the Therapeutic Gap?Biomedicines · 2026Review
- Exceptionally prolonged retention of a silicone-covered esophageal stent before TIPS for refractory variceal bleeding: a case report.Frontiers in medicine · 2026Article
- [Clinical outcomes of small-size grafts in auxiliary liver transplantation for the treatment of portal hypertension].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Commentary on "Preoperative carbohydrate loading reduces perioperative insulin resistance and hastens functional recovery of remnant liver after living donor hepatectomy: an open-label randomized controlled trial".Hepatology international · 2025Article
- Comments on: Addition of midodrine to albumin reduces the incidence of complications of large-volume paracentesis: an RCT comparing midodrine, terlipressin, and albumins.Hepatology international · 2025Article
- Commentary on "Addition of midodrine to albumin reduces the incidence of complications of large‑volume paracentesis: an RCT comparing midodrine, terlipressin, and albumin" : Midodrine-albumin: democratizing care for refractory ascites in resource-limited settings.Hepatology international · 2025Article
Corrections and comments
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Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute variceal bleeding (AVB) is a common life-threatening complication of portal hypertension (PHT), having a six-week mortality of 10%-20%. Major advances in the hemodynamic management, risk stratification, pharmacotherapy, endoscopy techniques, hemostatic devices and radiological interventions have led to improved management and outcome of AVB patients in the recent past. Therefore, the APASL Portal Hypertension Working Party, chose a panel of experts, primarily from the Asia-Pacific region, to identify important developments and controversial areas in the field of AVB. They discussed through a pre-defined and structured process, advances in the field and proposed updates to the previous APASL AVB guidelines. These included emphasis on safe transportation, defining time frames for AVB episodes and re-bleeding, reporting of clinical outcomes, optimizing early intervention strategies, pharmacotherapy, medical management, endoscopic therapies, and salvage modalities, including TIPS and self-expanding metal stents. The current updates also cover variceal bleeding in special populations and situations, the skill sets required for managing AVB patients, and the research priorities in the field. The updated guidelines are based on the latest evidence and incorporate emerging trends to provide a contemporary template for management of AVB in both patients with cirrhosis and non-cirrhotic portal hypertension.
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