Evidence map›Paper›PMID 40886187›Full record

ArticleEuropean journal of nutrition2025

Dietary vitamin D and gastric cancer risk within the stomach cancer pooling (stop) project.

Claudia Santucci, Arianna Natale, Claudio Pelucchi, Rossella Bonzi, Nuno Lunet, Samantha Morais, Jesús Vioque, Sandra González-Palacios, Nuria Aragonés, Gemma Castaño-Vinyals and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Claudia SantucciDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-9845-5307
Arianna NataleDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0001-5939-1999
Claudio PelucchiDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0003-1425-8945
Rossella BonziDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-2155-6126
Nuno LunetEPIUnit- Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.ORCID http://orcid.org/0000-0003-1870-1430
Samantha MoraisEPIUnit- Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.ORCID http://orcid.org/0000-0001-5808-0179
Jesús VioqueConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID http://orcid.org/0000-0002-2284-148X
Sandra González-PalaciosConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID http://orcid.org/0000-0003-3358-472X
Nuria AragonésConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID http://orcid.org/0000-0003-0983-2156
Gemma Castaño-VinyalsConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID http://orcid.org/0000-0003-4468-1816
Reza MalekzadehDigestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-9820-6335
Mohammadreza PaksereshtDigestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-1356-9135
Eva NegriDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0001-9712-8526
Paolo BoffettaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0002-3811-2791
M Constanza CamargoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.ORCID http://orcid.org/0000-0002-1065-2198
Maria Paula CuradoCentro Internacional de Pesquisa, A. C. Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8172-2483
Zuo-Feng ZhangDepartment of Epidemiology, School of Public Health and Jonsson Comprehensive Cancer Center, UCLA Fielding, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-4669-3995
Stefania BocciaSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID http://orcid.org/0000-0002-1864-749X
Carlo La VecchiaDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy. carlo.lavecchia@unimi.it.ORCID http://orcid.org/0000-0003-1441-897X
Marta RossiDepartment of Clinical Sciences and Community Health, Department of Excellence 2023-27, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-3822-9279

Funding

EPIUnit-Junior Research-Prog financing UIDP/04750/2020Fondazione AIRC per la ricerca sul cancro ETS 21378Fundação para a Ciência e a Tecnologia UIDB/04750/2020Fundo Europeu de Desenvolvimento Regional POCI-01- 0145-FEDER-032358Fundo Europeu de Desenvolvimento Regional Reference PTDC/SAU-EPI/32358/2017Generalitat Valenciana AICO/2021/347Laboratório para a Investigação Integrativa e translacional em Saúde Populacional ITRLaboratório para a Investigação Integrativa e translacional em Saúde Populacional LA/P/0064/2020Laboratório para an Investigação Integrativa e Translacional em Saúde Populacional ITRLaboratório para an Investigação Integrativa e Translacional em Saúde Populacional LA/P/0064/2020Ministero dell'Istruzione, dell'Università e della Ricerca 2022A4WZFC
6 · The paper itself

Abstract

purposeThe evidence regarding the role of vitamin D on gastric cancer (GC) is controversial. Within the Stomach cancer Pooling (StoP) Project, a global consortium of epidemiological studies on GC, we aimed to evaluate the relationship between dietary vitamin D and GC risk.

methodsFive case-control studies were included in the analysis, accounting for 1875 cases and 5899 controls. Odds ratios (OR) of GC and the corresponding 95% confidence intervals (CI) for tertiles of vitamin D intake were computed using logistic regression models adjusted for relevant confounders, including energy intake. The pooled ORs were computed using random-effect models.

resultsThe pooled OR of GC for the highest compared to the lowest tertile of vitamin D intake was 1.06 (95% CI 0.80-1.39), with a p for heterogeneity of 0.019. No significant association was found across strata of sex, age, socioeconomic status, smoking status, alcohol intake, and vegetable and fruit consumption.

conclusionsOur pooled analysis indicates that there is no association between dietary vitamin D and the risk of GC.

Indexed as

DietStomach NeoplasmsVitamin DAdultAgedCase-Control StudiesFemaleHumansLogistic ModelsMaleMiddle AgedOdds RatioRisk FactorsVitamin DDietary vitamin DEpidemiologyGastric cancerPooled analysis

Identifiers

PMID40886187
PMCPMC12399693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.