Evidence map›Paper›PMID 40886181›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Density and Maturity of Tertiary Lymphoid Structures Predict Clinical Outcome in Invasive Lung Adenocarcinoma.

Yanyan Huang, Fei Huang, Xinyue Zhang, Chunyan Li, Jinjin Lou, Liyun Xu

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In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanyan HuangCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China.ORCID 0000-0002-8491-7769
Fei HuangDepartment of Pathology, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China.
Xinyue ZhangZhoushan Hospital, Postgraduate Training Base Alliance of Wenzhou Medical University, Zhejiang, China.
Chunyan LiCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China.
Jinjin LouZhoushan Hospital, Postgraduate Training Base Alliance of Wenzhou Medical University, Zhejiang, China.
Liyun XuCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionTertiary lymphoid structures (TLSs) have been associated with the prognosis of various solid tumors. However, the association between TLSs and the prognosis of invasive lung adenocarcinoma (IAC) remains unclear in terms of location, density, and maturity.MethodsWe retrospectively reviewed the clinicopathological characteristics of 750 patients with IAC. The density of TLSs in various tumor regions, as well as their maturation status, was examined by pathologists. The X-tile software was employed to determine the optimal cut-off values for the intratumoral and peritumoral TLS density based on overall survival. A threshold of 1.33 TLSs/cm

Indexed as

Adenocarcinoma of LungLung NeoplasmsTertiary Lymphoid StructuresAdultAgedAged, 80 and overFemaleHumansKaplan-Meier EstimateLymphatic MetastasisMaleMiddle AgedNeoplasm InvasivenessPrognosisRetrospective Studiesclinicopathological characteristicsinvasive lung adenocarcinomaprognosistertiary lymphoid structurestumor microenvironment

Identifiers

PMID40886181
PMCPMC12399829

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.