Evidence map›Paper›PMID 40886081›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

The majority of elite and professional athletes return to the preinjury level of activity after anterior cruciate ligament reconstruction: A systematic review and meta-analysis.

Riccardo D'Ambrosi, Andrea Marchetti, Luca Farinelli, Amit Meena, Piero Franco, Luca Maria Sconfienza, Riccardo Cristiani, Elmar Herbst, Christoph Kittl, Mirco Herbort and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Riccardo D'AmbrosiIRCCS Ospedale Galeazzi - Sant'Ambrogio, Milan, Italy.ORCID https://orcid.org/0000-0002-1216-792X
Andrea MarchettiDepartment of Medicine, Surgery and Health Sciences, Orthopedics and Traumatology Unit, University of Trieste, Trieste, Italy.
Luca FarinelliClinical Orthopaedics Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.
Amit MeenaDepartment of Orthopaedics, Shalby Hospital, Jaipur, India.
Piero FrancoDepartment of Orthopedics Surgery, A.O.U. Careggi CTO, University of Florence, Florence, Italy.
Luca Maria SconfienzaIRCCS Ospedale Galeazzi - Sant'Ambrogio, Milan, Italy.
Riccardo CristianiDepartment of Molecular Medicine and Surgery, Section of Sports Medicine, Karolinska Institutet, Stockholm, Sweden.
Elmar HerbstDepartment of Trauma, Hand and Reconstructive Surgery, University of Muenster, Muenster, Germany.
Christoph KittlDepartment of Trauma, Hand and Reconstructive Surgery, University of Muenster, Muenster, Germany.
Mirco HerbortOCM Clinic Munich, Steinerstraße, Germany.
Elisabeth AbermannGelenkpunkt-Sports and Joint Surgery FIFA Medical Centre of Excellence, Innsbruck, Austria.
Christian FinkGelenkpunkt-Sports and Joint Surgery FIFA Medical Centre of Excellence, Innsbruck, Austria.

Funding

Italian Ministry of Health - "Ricerca Corrente"
6 · The paper itself

Abstract

purposeTo compare return to play (RTP), time to RTP, level of RTP, and anterior cruciate ligament (ACL) graft failure among elite and professional athletes from different sports after anterior cruciate ligament reconstruction (ACLR).

methodsThe PubMed, Embase and Cochrane Library databases were searched to identify potentially relevant research articles that analysed RTP, time to RTP, level of RTP, and graft failure rate in elite and professional athletes after ACLR. An elite or professional athlete was defined as one who participates in national- or international-level competitions in professional or amateur sports-including academy players aged 15 years or over.

resultsA total of 49 studies met the inclusion criteria. Eleven different sports and 4463 knees were included in the final analysis. The pooled data revealed an RTP rate of 85.8% (95% confidence interval [CI] 82.8-88.5]. A lower RTP was observed in Australian football (67.8% [95% CI 54.1-80.1]; p < 0.001) and football (73.0% [95% CI 65.9-79.5]; p < 0.001) than in soccer (92.8% [95% CI 89.3-95.7]). Almost 90% of the athletes returned to their preinjury level. The meta-analysis revealed no difference (p > 0.05) in the level of RTP rate among the different studies, ranging from 79.0% (soccer) to 97.3% (basketball). The pooled mean time to RTP was 292 days (95% CI 268-316 days). The pooled ACL graft failure rate was estimated to be 7.0% for athletes.

conclusionsFollowing ACLR, more than 85% of elite and professional athletes returned to play and almost 90% returned to their preinjury level, with a graft failure rate of 7.0% and a mean return to play at 292 days. Athletes and their treating physicians can utilise these findings to set reasonable expectations for their return to competition after ACLR. LEVEL OF EVIDENCE: Level IV systematic review and meta-analysis.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionAthletic InjuriesKnee InjuriesReturn to SportAthletesHumansRecovery of FunctionACLelite athletesfailure ratereturn to sportsame preinjury leveltime to return

Identifiers

PMID40886081
PMCPMC13327412

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.