ArticleJournal of ovarian research2025
Potential impact of air pollution on polycystic ovary syndrome incidence: a global analysis of 171 countries and regions from 1990 to 2021.
Article in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Identifying Potential Drivers of the Polycystic Ovary Syndrome Burden in the European Union: GBD 2023 SEV Exposure Profiling and Mendelian Randomization.International journal of women's health · 2026Article
- Spatiotemporal Heterogeneity and the Impact of PM1 and Nitrogen Oxides on Chronic Kidney Disease Mortality in 39 European Countries (1990-2022): A Multi-Model Analysis.International journal of nephrology and renovascular disease · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundAlthough polycystic ovary syndrome (PCOS) incidence is associated with air pollution, the relationship between air pollution, especially fluctuations in global NO₂ concentrations, and the burden of PCOS remains unclear. In this ecological study, we aimed to investigate this relationship using the Global Burden of Disease 2021 dataset.
methodsData on age-standardized incidence rates (ASIR) of PCOS were collected from 171 countries and regions over a 30-year period (1990-2021). Corresponding data on air pollution (NO₂, SO
resultsResults from the mixed linear models and geographic detectors showed that NO₂, SO₂, PM, and O₃ were associated with an increased ASIR of PCOS. Meanwhile, the mixed linear models further demonstrated a positive correlation between the incidence of PCOS and the concentration of air pollutants. In further investigating the relationship between NO₂ and PCOS, we found that the associations between the concentration of NO₂ and ASIR were non-linear (P for non-linear < 0.001). Moreover, the association between NO₂ and PCOS was more pronounced in regions with middle to high economic development.
conclusionsThe continuous presence and fluctuations in the concentrations of multiple air pollutants, particularly NO₂, may be potential contributors to the increasing burden of PCOS. These findings may suggest that improvements in air quality could be associated with a reduced burden of PCOS.
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