Evidence map›Paper›PMID 40885838›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026

Application of artificial intelligence in oral potentially malignant disorders: current opinions and future barriers.

Xuze Guo, Yaozu He, Qi Han, Jialin Xie, Yi Jia, You Li, Fanglong Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enhancing the therapeutic efficacy of tumor-treating fields (TTFields): further perspectives.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuze GuoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Yaozu HeState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Qi HanDepartment of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Jialin XieState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Yi JiaHigh-Technology Research and Development Center (NSFC), Beijing, 100044, China.
You LiThe Jinjiang Out-Patient Department, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. 125287728@qq.com.
Fanglong WuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. wufanglong@scu.edu.cn.ORCID http://orcid.org/0000-0003-4506-1387

Funding

College Students' Innovative Entrepreneurial Training Plan Program of Sichuan Province S202410610286National Key Research and Development Program of China 2023YFC3605600National Natural Science Foundation of China 82370963Sichuan Province Science and Technology Support Program 2023ZYD0104
6 · The paper itself

Abstract

Oral potentially malignant disorders (OPMDs) refer to oral mucosal disorders with an increased risk of malignancy, primarily oral squamous cell carcinoma (OSCC), especially in South and Southeast Asia. Since not all patients with OPMDs develop oral cancer, accurate early detection and diagnosis of malignant transformation are critically important for clinicians to determine the optimal therapeutic approach. Therefore, distinguishing OPMDs from early-stage OSCC is an increasing challenge in the clinic. Artificial intelligence (AI) technology has recently been shown to quickly identify high-risk conditions/lesions for screening oral cancer early. Moreover, the AI algorithm can also be used to determine the prognosis of OPMDs. In this review, we systematically summarize the medical records, oral images, pathological examinations, biomarkers, omics data and other aspects of the main outcomes of AI applied to address OPMDs-related issues. Furthermore, we discuss automated diagnostic systems and risk prediction tools for malignant transformation with pleasant outcomes and the potential to ultimately assist clinicians. Finally, we introduce the current challenges and barriers to AI in OPMDs on the premise that more advanced AI models and larger datasets will lead to the use of AI models in OPMDs.

Indexed as

Artificial IntelligenceCarcinoma, Squamous CellMouth NeoplasmsPrecancerous ConditionsEarly Detection of CancerHumansPrognosisArtificial intelligenceCancerMachine learningMedical diagnosisOral potentially malignant disordersPrediction methods

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.