Evidence map›Paper›PMID 40885827›Full record

ArticleScientific reports2025

Enhanced ground reaction force analyses reveal injury-related Biomechanical differences in runners.

Ryan M Nixon, Kevin R Vincent, Lydia Pezzullo, Heather K Vincent

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan M NixonDepartment of Physical Medicine and Rehabilitation, College of Medicine, Gainesville, FL, 112730, USA.ORCID http://orcid.org/0009-0000-0019-0850
Kevin R VincentThe Orthopaedic Institute, Alachua, FL, USA.ORCID http://orcid.org/0000-0003-3179-3464
Lydia PezzulloDepartment of Physical Medicine and Rehabilitation, College of Medicine, Gainesville, FL, 112730, USA.ORCID http://orcid.org/0009-0001-2295-2585
Heather K VincentDepartment of Physical Medicine and Rehabilitation, College of Medicine, Gainesville, FL, 112730, USA. heatherketelaar@gmail.com.ORCID http://orcid.org/0000-0003-2177-1683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This three-part study investigated alternative pre-processing techniques to better understand the differences in patterns of ground reaction force (GRF) and load rate (LR) among runners with running-related injury (RRI). 534 runners were assessed on an instrumented treadmill with 3D kinematic data capture. Participants were classified as "injured" or "uninjured" and "rearfoot" (RF) or "non-rearfoot" (non-RF) strikers. The raw net GRF is normalized by time and then averaged across at least ten steps for the left and right foot; a double Gaussian characterizes the biphasic double-mass-spring model of running gait. Six parameters from the Gaussians were used to describe the relative differences and shape change based on injury condition. LRs were calculated using a central difference numerical derivative of the raw normalized net force data. 32% of runners reached peak negative LR (unloading) within the first 20% of stance. Injured RF strikers had 18% higher peak positive LR and 6% shorter time to peak than uninjured RF strikers (p < 0.05). Injured non-RF strikers showed peak negative LR 10% earlier in normalized stance, with a 10% shorter interval between positive and negative peaks (p < 0.05). The magnitude and timing of impact and active phases of GRF waveforms differed in runners with history of tibial stress fractures and current Achilles tendinopathy (p < 0.05). LR and LR timing are important in relation to specific RRI. These alternative pre-processing methods may help improve mechanistic understanding of GRF and LR and identify gait retraining foci for specific injury diagnoses in the future.

Indexed as

RunningAdultBiomechanical PhenomenaFemaleFootGaitHumansMaleMiddle AgedYoung AdultGround reaction forceInjuryKineticsLoad rateRunning

Identifiers

PMID40885827
PMCPMC12398509

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.