ArticleCommunications biology2025
Gesture encoding in human left precentral gyrus neuronal ensembles.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Restoring rapid natural bimanual typing with a neuroprosthesis after paralysis.Nature neuroscience · 2026Article
- Learning-related population dynamics in right and left dorsal premotor cortex during typing skill acquisition.bioRxiv : the preprint server for biology · 2026Article
- Overlap in neural representations of coordinated wrist and finger movements in human motor cortex.bioRxiv : the preprint server for biology · 2026Article
- Pre-movement EEG microstates reflect intended lifted load of volitional movement.Frontiers in computational neuroscience · 2026Article
- Pseudo-linear summation explains neural geometry of multi-finger movements in human premotor cortex.Nature communications · 2025Article
- Multi-gesture drag-and-drop decoding in a 2D iBCI control task.Journal of neural engineering · 2025Article
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14 authors.
Funding
Abstract
Understanding the cortical activity patterns driving dexterous upper limb motion has the potential to benefit a broad clinical population living with limited mobility through the development of novel brain-computer interface (BCI) technology. The present study examines the activity of ensembles of motor cortical neurons recorded using microelectrode arrays in the dominant hemisphere of two BrainGate clinical trial participants with cervical spinal cord injury as they attempted to perform a set of 48 different hand gestures. Although each participant displayed a unique organization of their respective neural latent spaces, it was possible to achieve classification accuracies of ~70% for all 48 gestures (and ~90% for sets of 10). Our results show that single-unit ensemble activity recorded in a single hemisphere of human precentral gyrus has the potential to generate a wide range of gesture-related signals across both hands, providing an intuitive and diverse set of potential command signals for intracortical BCI use.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.