SynthesisBreast cancer (Tokyo, Japan)2025
The association between neighborhood socioeconomic status and breast cancer incidence and mortality risk: a large-scale cohort studies systematic review and meta-analysis.
Synthesis in Breast cancer (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Phosphorus Intake and Cancer Risk: A Theoretical-Conceptual Model and Hypothesis for Population-Study Replication.Nutrients · 2026Article
- DNAzyme-Based Nanostructures for Dynamic Cell Regulation and Sensing.ChemistryOpen · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBreast cancer (BC) remains one of the leading causes of cancer-related incidence and mortality globally, with growing evidence suggesting that neighborhood socioeconomic status (n-SES) can influence cancer incidence and survival. However, findings across studies remain inconsistent, and the extent to which n-SES impacts BC outcomes has not been comprehensively understood. A thorough systematic review and meta-analysis were conducted to assess the association of neighborhood socioeconomic status n-SES and BC incidence and mortality risk.
methodsA thorough investigation of existing literature was conducted by applying ISI Web of Science, PubMed/MEDLINE, and Scopus until June 08, 2025. Hazard ratios (HR), along with their respective 95% confidence intervals (CI), were integrated utilizing a random-effects model. A validated approach was utilized for assessing the quality of the studies and identification of publication bias, employing the Newcastle-Ottawa Scale for the assessment of quality, conducting subgroup analyses to identify potential sources of heterogeneity, and applying Egger's regression to detect publication bias and perform sensitivity analyses.
resultsA total of 17 studies with 779,352 adult subjects were found. The results revealed no association of significance among disadvantaged n-SES and BC incidence risk (HR = 1.19; 95% CI 0.86, 1.65; I
conclusionDisadvantaged n-SES is identified as a significant element to higher death rates related to BC. By understanding the root causes of inequalities in BC incidence and mortality across different socioeconomic environments, targeted interventions can be tailored to meet the specific needs of vulnerable individuals, ultimately leading toward improved BC outcomes for those at greatest risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.