Evidence map›Paper›PMID 40885228›Full record

ArticleThe Annals of thoracic surgery2025

Venous Thromboembolism After Coronary Artery Bypass Increases Health Care Costs: A Propensity Score-Matched Analysis.

Alex M Wisniewski, Mohamad El Moheb, Neha Polavarapu, Ariaz Goudarzi, Anthony V Norman, Sean Noona, Matthew P Weber, Mohammed Quader, Aditya Sharma, Nicholas R Teman

Abstract read
In one paragraph

Article in The Annals of thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alex M WisniewskiDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Mohamad El MohebDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Neha PolavarapuDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Ariaz GoudarziDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Anthony V NormanDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Sean NoonaDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Matthew P WeberDivision of Cardiothoracic Surgery, University of Virginia, Charlottesville, Virginia.
Mohammed QuaderDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia.
Aditya SharmaDivision of Vascular Medicine, Sanger Heart and Vascular Institute, Atrium Health, Charlotte, North Carolina.
Nicholas R TemanDivision of Cardiothoracic Surgery, Department of Surgery, University of Colorado, Aurora, Colorado. Electronic address: nicholasteman@gmail.com.

Funding

Cardiovascular Surgery Training ProgramT32HL007849 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI KRON, IRVING L., LAUBACH, VICTOR E · 1998 to 2025
$7.0M
NHLBI NIH HHS T32 HL007849
6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) after cardiac surgery is rare but may increase hospital resource utilization. We sought to determine the cost associated with development of VTE in patients undergoing isolated coronary artery bypass grafting (CABG).

methodsThe Society of Thoracic Surgeons data were identified for all patients undergoing isolated CABG between 2010 and 2020. VTE was defined as any deep venous thrombosis or pulmonary embolism occurring in-hospital during the index operation. Patients were propensity score matched by optimal full matching with threshold standard mean difference between -0.1 and 0.1. Cost analysis was performed on matched groups with a weighted linear regression model. A marginal effects analysis was used to determine total hospital costs.

resultsWe analyzed 18,159 patients, including 162 (0.9%) in whom VTE developed. Weighted linear regression found that VTE increased total index hospitalization cost by an average of $23,150 (P < .001), driven mostly by increases in intensive care unit expenditure ($12,640), pharmacy costs ($4649), and then step-down unit costs ($1719). The average inpatient hospital cost for a patient with VTE was $57,577 compared with $34,010 for those without VTE. This increased per-patient cost equated to approximately $3.8 million more for all patients with VTE after CABG during the study period.

conclusionsDevelopment of VTE after isolated CABG is associated with a significant increase in health care resource utilization driven by increased intensive care unit, pharmacy, and step-down unit costs. Centers without appropriate prophylaxis protocols should consider implementing one to best prevent this increase in resource utilization from development of this complication.

Indexed as

Coronary Artery BypassHealth Care CostsPostoperative ComplicationsPropensity ScoreVenous ThromboembolismAgedFemaleHospital CostsHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID40885228
PMCPMC12452196

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.