Evidence map›Paper›PMID 40884909›Full record

ArticleApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine2025

Automated production of radiotracer [

Lin Qiu, Christopher Bognar, Vijai Kumar Reddy Tangadanchu, Stephen M Moerlein, Gregory G Gaehle, Robert J Gropler, Joel S Perlmutter, Tammie L S Benzinger, Zhude Tu

Abstract read
In one paragraph

Article in Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lin QiuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States. Electronic address: linqiu@wustl.edu.
Christopher BognarDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Vijai Kumar Reddy TangadanchuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Stephen M MoerleinDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Gregory G GaehleDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Robert J GroplerDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Joel S PerlmutterDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States; Department of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Tammie L S BenzingerDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States.
Zhude TuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri, 63110, United States. Electronic address: zhudetu@wustl.edu.

Funding

Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Robert J. Gropler · 2018 to 2026
$12.7M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
Investigate neuroinflammation in the brain of PD using S1P1 radioligandsR01NS134586 · NINDS · WASHINGTON UNIVERSITY · PI JOEL Synes PERLMUTTER, Zhude Tu · 2024 to 2026
$1.8M
NIBIB NIH HHS P41 EB025815NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS134586
6 · The paper itself

Abstract

We report a reliable fully automated procedure to produce a promising F-18 labeled sphingosine-1-phosphate receptor 1 (S1PR1) PET ligand, 3-((2-fluoro-4-(5-(4-(2-(fluoro-

Indexed as

Fluorine RadioisotopesOxadiazolesRadiopharmaceuticalsSphingosine-1-Phosphate ReceptorsAutomationHumansPositron-Emission TomographyFluorine-18Fluorine RadioisotopesOxadiazolesRadiopharmaceuticalsS1PR1 protein, humanSphingosine-1-Phosphate Receptors[(18)F]FZTAAutomated radiosynthesiscGMPFluorine-18Positron emission tomographySphingosine-1-phosphate receptor 1

Identifiers

PMID40884909
PMCPMC13108123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.