ArticleJournal of veterinary internal medicine
Treatment of Naproxen Overdose Using Therapeutic Plasma Exchange and Plasmaperfusion in a Dog.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Treatment of Naproxen Overdose Using Therapeutic Plasma Exchange and Plasmaperfusion in a Dog.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An 8-year-old male neutered 37.4 kg mixed breed dog was presented for suspected ingestion of a large amount of naproxen (estimated at 235-294 mg/kg). The dog was treated using a combination of therapeutic plasma exchange (TPE) and plasmaperfusion (PP). The exchange of 2 plasma volumes during 140 min of TPE resulted in a 46% decrease in blood naproxen concentration. Treatment of 1 plasma volume during the following 90 min of PP resulted in an additional 10.3% decrease in naproxen concentration. The patient developed mild gastrointestinal (GI) signs that were treated medically and was successfully discharged after 4 days of hospitalization with normal follow-up laboratory test results and physical examination findings. The combination of extracorporeal treatments decreased the plasma concentration of naproxen, but the additional decrease from PP may not have provided substantial benefit compared with other conventional treatments. No reports of PP, as an alternative to hemoperfusion (HP), in veterinary medicine currently are available.
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