Evidence map›Paper›PMID 40884734›Full record

ArticleInternational journal of computer assisted radiology and surgery2026

A multicenter study on the comparability of myocardial strain values acquired with different CMR scanners and analyzed with different post-processing software: insights into the "Traveling Volunteers" study.

Collin Goetze, Wensu Chen, Patrick Doeblin, Aylin Demir, Stephanie Wiesemann, Jochen Hansmann, Volkmar Falk, Jeanette Schulz-Menger, Jennifer Erley, Sebastian Kelle

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Regional strain patterns in patients with mitral valve prolapse.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  2. Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Collin Goetze *Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Virchow-Klinikum Augustenburger Platz 1, 13353, Berlin, Germany.
Wensu Chen *Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, 99 Huaihai West Road, Xuzhou, 221002, China.
Patrick DoeblinDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Virchow-Klinikum Augustenburger Platz 1, 13353, Berlin, Germany.
Aylin DemirDepartment of Cardiology and Nephrology, Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a Joint Cooperation Between the Charité-Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, and the Max-Delbrueck Center for Molecular Medicine, HELIOS Klinikum Berlin Buch, Berlin, Germany.
Stephanie WiesemannDepartment of Cardiology and Nephrology, Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a Joint Cooperation Between the Charité-Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, and the Max-Delbrueck Center for Molecular Medicine, HELIOS Klinikum Berlin Buch, Berlin, Germany.
Jochen HansmannDepartment of Radiology, Theresienkrankenhaus Und St. Hedwig-Klinik, Mannheim, Germany.
Volkmar FalkDZHK (German Center for Cardiovascular Research), Partner Site Berlin, 13353, Berlin, Germany.
Jeanette Schulz-MengerGerman Center for Cardiovascular Research (DZHK), Berlin, Germany.
Jennifer Erley *Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-4855-7698
Sebastian Kelle *Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Virchow-Klinikum Augustenburger Platz 1, 13353, Berlin, Germany. sebastian.kelle@dhzc-charite.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStrain quantifies myocardial deformation. Despite its high diagnostic value, strain analyses using cardiovascular magnetic resonance (CMR) feature tracking (FT) have not been fully implemented into clinical routine due to lack of information on reproducibility. The purpose of this study was to assess the comparability of cardiovascular magnetic resonance CMR FT strain and ejection fraction (EF) measurements, obtained from different MR scanners and analyzed using different software platforms.

methodsCMR examinations were performed in 15 healthy volunteers using three different scanners (German Heart Center of the Charité, Charité Campus Berlin Buch, and Theresien-Hospital Mannheim). FT was performed using Medis Suite and Circle CVI. Inter-software/scanner agreement was determined using Bland-Altman plots, Wilcoxon test, and paired Student's t test. Intra-/inter-observer reproducibility was evaluated using intraclass correlation coefficients.

resultsLeft ventricular (LV) global longitudinal (GLS) and circumferential (GCS) strain did not differ between the three centers (small bias of - 1.27 to 1.32% for GLS and 0.91 to 0.69% for GCS). Inter-scanner agreement was lower regarding LV global radial strain (GRS) (bias of - 2.29 to 4.53%) and good for LV EF (bias of - 0.59 to 0.94%). Inter-software agreement was low for GLS (bias of - 5.72 to - 4.59%), GCS (- 1.13 to - 1.55%), and GRS (18.34 to 19.83%), with higher GLS/GCS and lower GRS values in CVI than Medis. LV EF showed better inter-software agreement (biases of - 0.07 to 0.06%). Intra- and inter-observer reproducibility was good for strain measurements across all scanners (bias of - 0.01 to 2.05 and 0.22 to 1.92, respectively) and software packages (ICC 0.70 to 0.90 and 0.51 to 0.89, respectively).

conclusionInter-scanner reproducibility for CMR FT measurements was high for GLS and GCS, suggesting potential use in routine CMR examinations. However, strain values between the two software vendors (CVI and Medis) were significantly different, indicating the need for standardization and implementation of software-specific cutoff values.

Indexed as

Magnetic Resonance ImagingMagnetic Resonance Imaging, CineSoftwareAdultFemaleHealthy VolunteersHumansMaleMiddle AgedObserver VariationReproducibility of ResultsStroke VolumeVentricular Function, LeftCardiovascular magnetic resonanceFeature trackingMulticenterStrain

Identifiers

PMID40884734
PMCPMC13013134

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.