Evidence map›Paper›PMID 40884714›Full record

ArticleNeuroscience bulletin2026

Mitophagy Activation by N-Acetylcysteine Protects against Mic60 Deficiency-Induced Auditory Neuropathy.

Yilin Sun, Chunying Liu, Yakun Liang, An Lv, Wang Nie, Shuyue Bao, Xiaoyi Li, Jing Zhou, Weimin Tong, Yong Tao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yilin Sun *Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Chunying Liu *Center for Experimental Animal Research, Institute of Basic Medical Sciences, Chinese Academy of Medical Science, Beijing, 100005, China.
Yakun Liang *Shanghai Institute of Precision Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China.
An LvCenter for Experimental Animal Research, Institute of Basic Medical Sciences, Chinese Academy of Medical Science, Beijing, 100005, China.
Wang NieDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Shuyue BaoDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Xiaoyi LiBiobank of Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China.
Jing ZhouBiobank of Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China.
Weimin TongDepartment of Pathology, Institute of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, 100005, China.
Yong TaoDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. taoyent@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-1351-2094
Xueling WangBiobank of Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China. wangxueling@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-6310-0071
Tingting DongBiobank of Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China. dtt623@sjtu.edu.cn.ORCID http://orcid.org/0009-0001-5797-1591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Auditory neuropathy (AN) is a sensorineural hearing loss that impairs speech perception, but its mechanisms and treatments remain limited. Mic60, essential for the mitochondrial contact site and cristae organizing system, is linked to neurological disorders, yet its role in the auditory system remains unclear. We demonstrate that Mic60

Indexed as

AcetylcysteineHearing Loss, CentralMitophagyAnimalsDisease Models, AnimalEvoked Potentials, Auditory, Brain StemMiceMice, Inbred C57BLMitochondriaSpiral GanglionAcetylcysteineAntioxidantAuditory neuropathyMic60MitochondriaMitophagyN-acetylcysteine

Identifiers

PMID40884714
PMCPMC12950139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.