SynthesisHeart failure reviews2025
Infective endocarditis complicated by shock: a systematic review and meta-analysis.
Synthesis in Heart failure reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- ICU-specific determinants of mortality in critically ill patients with infective endocarditis : Mortality predictors in ICU patients with infective endocarditis.BMC infectious diseases · 2026Article
- Clinical Experience of Ceftaroline Fosamil in Gram-Positive Infective Endocarditis: A Multicenter Real-World Observational Study.Antibiotics (Basel, Switzerland) · 2026Article
- Article
- Infective Endocarditis and Complications; Surgical Indications and Management: An Integrative Review.Journal of personalized medicine · 2026Review
- Precipitants of Acute Heart Failure: A State-of-the-art Review from an International Expert Group.Cardiac failure review · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infective endocarditis (IE) complicated by septic or cardiogenic shock is linked to a marked increase in morbidity and mortality rates. This systematic review and meta-analysis sought to evaluate clinical outcomes, identify prognostic factors, and assess the effects of valve surgical intervention in patients with infective endocarditis complicated by shock. Systematic searches were performed in PubMed, Cochrane Library, and Google Scholar databases, following PRISMA and MOOSE guidelines. Included were observational studies published from January 2015 to May 2025 that reported on adult patients with infective endocarditis complicated by septic or cardiogenic shock. A random-effects model was utilized for data synthesis (restricted maximum likelihood with Hartung-Knapp adjustment), and meta-regression was conducted to assess sources of heterogeneity. Seven observational studies were included (n = 183-255,838). In-hospital mortality among patients with shock was 62.3% (95% CI 48.3-74.5%). Compared with IE without shock, the pooled odds ratio for in-hospital mortality (HK-REML) was 5.83 (95% CI 1.35-25.23; 95% prediction interval 0.26-129.69), with substantial heterogeneity (I
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Registered trials
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