ReviewMethods in molecular biology (Clifton, N.J.)2025
The Fate of Micronuclei.
Review in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
This chapter provides a brief overview about micronuclei and their postmitotic fate. Micronuclei are small chromatin-containing bodies formed during mitosis and located in the cytoplasm. Micronuclei have been known for more than 100 years and used as biomarkers for decades, but their fate after formation and with that their biological relevance for the organism has only been addressed in recent years. Four major fates of micronuclei are known: extrusion, reincorporation, degradation, and persistence. Generally, most micronuclei persist without any changes. Around one quarter of the micronuclei are reincorporated into the main nucleus during one of the next mitoses. Degradation and extrusion only occur rarely under special circumstances. Mechanistic backgrounds are still not well understood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.