ReviewMethods in molecular biology (Clifton, N.J.)2025
Chromoanagenesis and Beyond: Catastrophic Events Shaping the Genome.
Review in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
The phenomena of chromoanagenesis have profoundly changed our conceptions regarding the genesis and etiology of complex rearrangements. These chaotic genomic events have also led to a better understanding of the mechanisms underlying the maintenance and fluctuations of genomic stability. Chromoanagenesis phenomena are now recognized as important drivers of karyotypic evolution, both in cancer and in developmental disorders. They question the conventional view of gradual evolution, supporting the role of genomic chaos in rapid evolutionary transitions.The advent of new genome sequencing technologies and their use in combination with powerful bioinformatics tools or single-cell analysis techniques have led to a better understanding of the complexity and heterogeneity of chromoanagenesis and to the description of new forms of complex and chaotic genomic rearrangements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.