Observational studyInternational ophthalmology2025
Long-term outcomes of vitrectomy for proliferative diabetic retinopathy: a real world study in China.
Observational study in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Construction and Validation of a Long-Term Visual Prognosis Prediction Model for Proliferative Diabetic Retinopathy After Vitrectomy Based on Machine Learning.Endocrinology, diabetes & metabolism · 2026Article
- Preoperative anti-VEGF and the cumulative risk of post-operative vitreous hemorrhage in PDR: a 2-year survival analysis and evaluation of surgical burden.International journal of retina and vitreous · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo investigate long-term outcomes and their predictive factors in Chinese patients with proliferative diabetic retinopathy (PDR) after vitrectomy. STUDY
designRetrospective and observational.
methodsPDR patients who underwent vitrectomy in a tertiary eye hospital from 2010 to 2020 were enrolled. The cumulative incidences of re-vitrectomy in the primary eye, vitrectomy in the contralateral eye, low vision (< 0.3 Snellen), and postoperative complications were calculated.
resultsA total of 1094 patients were included in the analysis. The 1-, 3-, and 5-year cumulative incidences for low vision in both eyes were 18.9%, 34.7%, and 44.4%, respectively. The 1-, 5-, and 10-year cumulative incidences for re-vitrectomy in the primary eye were 7.4%, 9.9%, and 9.9%, respectively, and for vitrectomy in the contralateral eye were 31.0%, 62.7%, and 79.5%, respectively. Vitrectomy in the contralateral eye was associated with younger age (hazard ratio [HR] = 0.99, 95% confidence interval [CI] 0.98-0.99), higher glycated hemoglobin (HR = 1.17, 95% CI 1.08-1.27), no preoperative photocoagulation (HR = 0.55, 95% CI 0.39-0.78), severer diabetic retinopathy level (HR = 2.28, 95% CI 1.56-3.33), and poorer preoperative vision (HR = 1.35, 95% CI 1.14-1.61). The cumulative postoperative incidences of the primary eye at 1, 5, and 10 years were 5.7%, 9.9%, and 9.9% for vitreous hemorrhage, 4.2%, 5.1%, and 5.1% for retinal detachment, and 2.8%, 6.2%, and 8.1% for neovascular glaucoma, respectively.
conclusionThis study reported a comprehensive post-vitrectomy incidence and predictive factors in Chinese PDR patients in a long-term follow up. This would aid in the clinical understanding of this lifelong disease.
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