Evidence map›Paper›PMID 40884528›Full record

ReviewEpilepsia open2025

The role of neuropsychology in stereo-EEG: A narrative review.

Emily Cockle, Charles B Malpas, Rubina Alpitsis, Terence J O'Brien, Genevieve Rayner, Andrew Neal

Abstract readReview
In one paragraph

Review in Epilepsia open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily CockleDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0003-3289-2181
Charles B MalpasDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0003-0534-3718
Rubina AlpitsisDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.
Terence J O'BrienDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.
Genevieve RaynerDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-0747-3877
Andrew NealDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-9251-5471

Funding

Australian Epilepsy Research FundAustralian Government Research Training Program scholarshipNHMRC Investigator Grant APP1176426NHMRC Investigator Grant APP2008737NHMRC Investigator Grant APP2009152
6 · The paper itself

Abstract

Stereo-EEG is accompanied by unique neuropsychological challenges in the workup, during the admission, and following the procedure. While established principles from epilepsy surgery programs provide a guiding framework for clinical practice, specialized guidelines to inform the role of neuropsychology in stereo-EEG warrant further consideration. In this review, we consider the role of neuropsychological assessments in assisting with localization of the epileptogenic network in the context of discordant noninvasive investigations, the paucity of research examining the cognitive risks associated with radiofrequency thermocoagulation, and the role for neuropsychological counseling in stereo-EEG. Through a narrative review, we then critically appraise the current literature surrounding the challenges of cognitive examination during cortical stimulation and subsequent clinical interpretation of elicited deficits. Overall, we propose a model of practice for clinical neuropsychology within stereo-EEG programs that includes neuropsychological assessment, neuropsychological counseling, and neuropsychological involvement for cortical stimulation. PLAIN LANGUAGE SUMMARY: Stereo-EEG is a complex investigative procedure that may be undertaken in people with drug-resistant epilepsy. Clinical neuropsychologists can help assess the cognitive risks and benefits associated with the procedure, in turn supporting patients to make informed decisions about their treatment options. Despite this, the role of clinical neuropsychology in stereo-EEG programs has been largely overlooked. As such, we propose a framework that highlights the clinical utility of neuropsychology before, during, and after stereo-EEG.

Indexed as

Drug Resistant EpilepsyElectroencephalographyEpilepsyNeuropsychologyStereotaxic TechniquesHumansNeuropsychological Testscognitive mappingdrug‐resistant epilepsyneuropsychological assessmentneuropsychological rehabilitationRFTHCSEEG

Identifiers

PMID40884528
PMCPMC12514387

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.