Evidence map›Paper›PMID 40884525›Full record

ArticleJACC. Asia2025

Atrial Fibrillation Detected by Handheld ECG and Ischemic Stroke Risk in a 55- to 64-Year-Old Chinese Population.

Wen Sun, Ben Freedman, Carlos Martinez, Christopher Wallenhorst, Christy K Y Chan, Bryan P Yan

Abstract read
In one paragraph

Article in JACC. Asia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen SunDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital & Heart & Vascular Institute, The Chinese University of Hong Kong, Hong Kong.
Ben FreedmanHeart Research Institute, Charles Perkins Centre, University of Sydney, Sydney, Australia.
Carlos MartinezInstitute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany.
Christopher WallenhorstInstitute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany.
Christy K Y ChanSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
Bryan P YanDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital & Heart & Vascular Institute, The Chinese University of Hong Kong, Hong Kong. Electronic address: bryan.yan@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) screening is recommended at age ≥65 years, but the age threshold in Asians is uncertain because of higher ischemic stroke risk <65 years.

objectivesThis study evaluated AF screening yield in a Chinese population aged 55 to 64 years, comparing stroke risk of those with and without AF, and the effect of oral anticoagulants (OAC).

methodsPatients aged 55 to 64 years attending Hong Kong outpatient clinics underwent opportunistic handheld electrocardiogram screening. Repeat screening was performed if >1 clinic visits. Crude incidence rate ratios of ischemic stroke were determined and compared between 3 cohorts: screen-detected AF; clinically diagnosed AF; and no AF. Ischemic stroke risk for all AF categories was compared with individuals without AF, using adjusted subdistribution HRs (aSHRs) accounting for death as a competing risk.

resultsOf 3,926 subjects screened, 338 (8.6%) had known AF, and 3,588 had no AF history. New AF yield was 0.8% (28/3,588). AF was clinically diagnosed during follow-up in 2.3% (n = 82) and during subsequent screening in 7 subjects. Of 35 subjects with screen-detected AF, 26 (74%) had ≥1 non-age, non-sex risk factor for stroke, mean age 60.8 ± 2.5 years, and mean CHA

conclusionsAlthough diagnostic yield of AF screening in Chinese patients aged 55 to 64 years is low, those with AF are at increased stroke risk and may warrant being on anticoagulation.

Indexed as

AFscreeningstroke

Identifiers

PMID40884525
PMCPMC12673832

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