Evidence map›Paper›PMID 40884242›Full record

ArticleJournal of investigative medicine high impact case reports

A Fatal Case of Acute Necrotizing Pancreatitis Following a COVID-19 Vaccine.

D'Argent Louise, Lormans Piet, Dumoulein Alexander, Schockaert Bernard

Abstract readCase Reports
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D'Argent LouiseEmergency Medicine Resident, UZ Leuven-Gasthuisberg, Belgium.ORCID 0000-0001-6631-5273
Lormans PietIntensive Care Medicine, AZ Delta Rumbeke, Belgium.
Dumoulein AlexanderIntensive Care Medicine, AZ Delta Rumbeke, Belgium.
Schockaert BernardIntensive Care Medicine, AZ Delta Rumbeke, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several adverse effects have been reported following the use of the Pfizer-BioNTech mRNA vaccine against COVID-19 infection with acute pancreatitis being one of those. However, a direct relationship between the vaccine and the occurrence of acute pancreatitis has not been confirmed. Hereby, a case of an acute necrotizing pancreatitis resulting in fatal outcome following the administration of the COVID-19 BioNTech Pfizer vaccine is presented. A 70-year-old male presented with abdominal pain 4 days after receiving his fifth dose of the COVID-19 BioNTech Pfizer vaccine. Laboratory examination showed lipase levels of 2000 U/L. A CT scan was performed and showed necrotizing pancreatitis. After detailed evaluation, no etiological cause of pancreatitis could be found in this patient. The patient was admitted to the intensive care unit. After a disease course of ~6 weeks, the patient died due to multiorgan failure. This case presentation takes into account previously reported cases of acute pancreatitis following COVID-19 vaccination. To our knowledge, this is the first case of acute pancreatitis with fatal ending following a COVID-19 vaccination. This highlights the importance of thorough evaluation of patients presenting with abdominal pain following the administration of a COVID-19 vaccine.

Indexed as

COVID-19COVID-19 VaccinesPancreatitis, Acute NecrotizingAgedFatal OutcomeHumansMaleSARS-CoV-2Tomography, X-Ray ComputedCOVID-19 Vaccinescase fatalityCOVID-19 vaccinegastroenterologyinfectiologypancreatic necrosispost-vaccination adverse eventpulmonary critical careradiology/imagingsevere pancreatitis

Identifiers

PMID40884242
PMCPMC12399823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.