Evidence map›Paper›PMID 40884209›Full record

ArticleEuropean journal of pain (London, England)2025

Experimental Pain Model Based on Short-Wave Diathermy Replicates the Intensity, Quality and Spatial Distribution of Chronic Shoulder Pain: A Parallel Group Validation Study.

Leonardo Intelangelo, Christian Ariel Mista, Mauro Barone, Fernando Imaz, Silvio Jorge Laugero, Javier Adur, Ole Kæseler Andersen, José Alberto Biurrun Manresa

Abstract readValidation Study
In one paragraph

Article in European journal of pain (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Leonardo IntelangeloUniversity Center for Assistance, Teaching and Research (CUADI), University of Gran Rosario, Rosario, Argentina.
Christian Ariel MistaInstitute for Research and Development on Bioengineering and Bioinformatics (IBB), CONICET-UNER, Oro Verde, Argentina.
Mauro BaroneUniversity Center for Assistance, Teaching and Research (CUADI), University of Gran Rosario, Rosario, Argentina.
Fernando ImazUniversity Center for Assistance, Teaching and Research (CUADI), University of Gran Rosario, Rosario, Argentina.
Silvio Jorge LaugeroLaboratory of Electromagnetic Fields in Biomedical Applications (LACEMAB), National University of Entre Ríos (UNER), Oro Verde, Argentina.
Javier AdurInstitute for Research and Development on Bioengineering and Bioinformatics (IBB), CONICET-UNER, Oro Verde, Argentina.
Ole Kæseler AndersenCenter for Neuroplasticity and Pain (CNAP), Faculty of Medicine, Aalborg University (AAU), Aalborg, Denmark.
José Alberto Biurrun ManresaInstitute for Research and Development on Bioengineering and Bioinformatics (IBB), CONICET-UNER, Oro Verde, Argentina.ORCID https://orcid.org/0000-0003-4060-9665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral experimental pain models have been developed to better understand shoulder pain. However, most of these models do not accurately replicate characteristic features of clinical pain. The aim of this study was to assess whether the effects of the short-wave diathermy (SWD) pain model mimic clinical shoulder pain in terms of intensity, quality, and spatial distribution.

methodsThirty-two patients with unilateral shoulder pain (USP) and thirty-two healthy volunteers participated in a single experimental session. SWD was applied to the dominant shoulder of healthy volunteers, until volunteers reached the tolerance threshold for painful heat stimulation. Pressure pain thresholds (PPTs), pain intensity (using a visual analogue scale, VAS), pain quality (using the McGill Pain Questionnaire) and spatial pain distribution were assessed 30 min after SWD application on the infraspinatus muscle. The same assessments were performed in the USP group. Outcomes were contrasted using linear mixed models and independent sample t tests, and statistical equivalence was assessed using the TOST (two one-sided t tests) procedure.

resultsPPTs on the painful side were statistically equivalent within a range of ±50 kPa. Pain intensities in both groups were statistically equivalent within a range of ±2 VAS points. Both groups showed a similar spatial pain distribution, and described the pain as continuous, well-delimited, dull and bearable. However, USP patients more frequently used the stabbing and nagging descriptors in contrast to volunteers in the SWD group, who chose hot and heavy instead.

conclusionExperimental pain induced by SWD accurately reproduces many relevant characteristics of chronic shoulder pain. SIGNIFICANCE STATEMENT: Short-wave diathermy applied to the shoulder of healthy volunteers elicited equivalent pain intensity, quality and spatial distribution compared with clinical unilateral shoulder pain.

Indexed as

Chronic PainDiathermyShoulder PainAdultFemaleHumansMaleMiddle AgedPain MeasurementPain ThresholdYoung Adultequivalence testingexperimental pain modelmusculoskeletal pain

Identifiers

PMID40884209
PMCPMC12397899

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.