Evidence map›Paper›PMID 40884069›Full record

ArticlePhysiological reports2025

Seasonal variations in ventricular repolarization and tachyarrhythmias in hibernating brown bears (Ursus arctos arctos).

Lucas Alexander Lindberg, Boris Fuchs, Alina Lynn Evans, Timothy Laske, Anna Björkenheim, Ole Fröbert, Lisa Amalie Gottlieb

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucas Alexander LindbergDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0000-0267-2511
Boris FuchsDepartment of Forestry and Wildlife Management, Faculty of Applied Ecology and Biotechnology, Inland Norway University of Applied Sciences, Koppang, Norway.
Alina Lynn EvansDepartment of Forestry and Wildlife Management, Faculty of Applied Ecology and Biotechnology, Inland Norway University of Applied Sciences, Koppang, Norway.
Timothy LaskeMedtronic Inc., Mounds View, Minnesota, USA.
Anna BjörkenheimDepartment of Cardiology, School of Medical Sciences, Örebro University, Örebro, Sweden.ORCID 0000-0002-4288-3310
Ole FröbertDepartment of Cardiology, School of Medical Sciences, Örebro University, Örebro, Sweden.
Lisa Amalie GottliebDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8121-4275

Funding

Branco Weiss Fellowship - Society in Science 2024BRIDGE Translational Excellence Programme NNF20SA0064340Danish Cardiovascular Academy NNF20SA0067242
6 · The paper itself

Abstract

In humans, hypothermia prolongs ventricular repolarization and associates with sustained ventricular tachyarrhythmias. In bears, body temperature drops during hibernation similar to moderate human hypothermia, yet they rarely face fatal outcomes during the winter. This suggests protective adaptations in bear electrophysiology. We studied seasonality in ursine ventricular repolarization by analyzing >1 year electrocardiogram (ECG) recordings from loop recorders implanted in 57 free-ranging Eurasian brown bears. In sinus rhythm, bears exhibited significantly longer RR, QT, and T

Indexed as

Heart VentriclesHibernationSeasonsTachycardiaUrsidaeAnimalsElectrocardiographyFemaleHeart RateMalebrown bearelectrocardiographyelectrophysiologyhibernationQT intervalventricular tachyarrhythmias

Identifiers

PMID40884069
PMCPMC12397579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.