Evidence map›Paper›PMID 40883994›Full record

ArticleFEBS open bio2026

Key role for inhibins in effective T cell activation, migration and Th17 differentiation.

Sandra Ortega-Francisco, Roxana Olguín-Alor, Lizbeth Bolaños-Castro, Alexandra Morales-Cruz, Marisol De La Fuente-Granada, Gloria Soldevila

Abstract read
In one paragraph

Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra Ortega-FranciscoDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.ORCID https://orcid.org/0000-0002-4275-8253
Roxana Olguín-AlorDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.
Lizbeth Bolaños-CastroDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.
Alexandra Morales-CruzDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.
Marisol De La Fuente-GranadaDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.
Gloria SoldevilaDepartamento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico.ORCID https://orcid.org/0000-0003-1539-2548

Funding

Universidad Nacional Autonoma de Mexico IN213319Universidad Nacional Autonoma de Mexico IN220124
6 · The paper itself

Abstract

Our group has previously reported that inhibin and its molecular pair, TGF-β type III receptor (TβRIII), regulate T cell development within the thymus. In addition, inhibins play a key role in immune tolerance through the modulation of dendritic cell (DC) maturation and peripheral Treg induction. However, the functional role of inhibins in T cell activation and differentiation is currently unknown. Here, we demonstrate that inhibins are produced by activated T cells and play a role during T cell activation, migration, and functional Th differentiation. Specifically, stimulation of Inhα

Indexed as

InhibinsLymphocyte ActivationTh17 CellsT-LymphocytesAnimalsCell DifferentiationCell MovementDendritic CellsMiceMice, Inbred C57BLMice, KnockoutInhibinsactivationinhibinsmigrationT cellsTh1/T17

Identifiers

PMID40883994
PMCPMC12767762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.