Evidence map›Paper›PMID 40883871›Full record

ArticleMagnetic resonance in medicine2026

Evaluating the effectiveness of distortion self-correction for CEST-EPI.

Yang Liu, Se Weon Park, Lok Hin Law, Kexin Wang, Licheng Ju, Jiadi Xu, Kannie W Y Chan, Jianpan Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang LiuDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0420-2211
Se Weon ParkDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.ORCID 0000-0002-4794-0388
Lok Hin LawDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.ORCID 0000-0002-7829-370X
Kexin WangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-0124-0631
Licheng JuF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.ORCID 0000-0002-3695-6843
Jiadi XuF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.ORCID 0000-0001-9698-5622
Kannie W Y ChanDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.ORCID 0000-0002-7315-1550
Jianpan HuangDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0002-4453-8764

Funding

City University of Hong Kong 7005626City University of Hong Kong 7030012City University of Hong Kong 9609321City University of Hong Kong 9610616Health and Medical Research Fund 21222621Innovation and Technology Commission - InnoHK - Hong Kong Centre for Cerebro-cardiovascular Health EngineeringInnovation and Technology Fund (Hong Kong) MHP/076/23National Natural Science Foundation of China 82402225Research Grants Council (Hong Kong) 11102218Research Grants Council (Hong Kong) 11200422Research Grants Council (Hong Kong) CityUHK RFS2223-1S02State Key Laboratory of Terahertz and Millimeter WavesTung Biomedical Sciences CentreUniversity of Hong Kong 109000487University of Hong Kong 204610401University of Hong Kong 204610519University of Hong Kong 2409100331
6 · The paper itself

Abstract

purposeEPI is a fast acquisition sequence, but suffers from geometric distortion because of B

methodsCEST MRI usually requires B

resultsDISC-CEST-EPI showed higher SSIM and spatial consistency compared to CEST-EPI when using CEST-rapid acquisition with relaxation enhancement as a reference in vitro and in vivo at 3 T. For in vivo experiments at 11.7 T, SSIM values of amide proton transfer and relayed nuclear Overhauser effects maps of DISC-CEST-EPI were slightly higher than CEST-EPI and comparable with field-mapping and top-up.

conclusionDISC-CEST-EPI can correct the distortion in CEST-EPI at 3 T, leading to improved SSIM and CEST quantification. This approach has the potential to enhance image quality and improve diagnostic accuracy for single-shot CEST-EPI at especially low-field MRI. However, the performance of DISC-CEST-EPI is limited at 11.7 T, and further advancements are necessary to enhance its functionality at ultra-high fields.

Indexed as

Echo-Planar ImagingImage Processing, Computer-AssistedAlgorithmsAnimalsBrainCreatineMagnetic Resonance ImagingMicePhantoms, ImagingReproducibility of ResultsCreatineCESTdistortionEPIself‐correctionΔB0 map

Identifiers

PMID40883871
PMCPMC12620148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.