Evidence map›Paper›PMID 40883863›Full record

ArticleVeterinary ophthalmology2025

Validation of the EYEMATE-SC Suprachoroidal Pressure Transducer for Telemetric Measurement of Intraocular Pressure in Normal Ex Vivo Canine and Equine Globes-Preliminary Results.

Phillip N Buckman, Bailey A Brinker, Lydia E Kapeller, András M Komáromy

Abstract readValidation Study
In one paragraph

Article in Veterinary ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Phillip N BuckmanDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.ORCID https://orcid.org/0009-0001-4452-0636
Bailey A BrinkerDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
Lydia E KapellerDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
András M KomáromyDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.ORCID https://orcid.org/0000-0002-8845-0588

Funding

Development of an IOP-lowering gene therapy treatment for glaucomaR01EY032478 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI KOMAROMY, ANDRAS, LIPINSKI, DANIEL MARK · 2022 to 2025
$2.6M
NEI NIH HHS R01 EY032478NIH HHS R01-EY032478
6 · The paper itself

Abstract

objectiveTo determine the accuracy of the EYEMATE-SC suprachoroidal tracer for telemetric tonometry in canine and equine globes. PROCEDURES: The EYEMATE-SC sensor (7.8 mm × 3.8 mm × 1 mm) was implanted in the suprachoroidal space of four freshly enucleated normal canine and two normal equine eyes. The anterior chambers were cannulated and connected to a reservoir of Plasma-Lyte A and a manometer. Starting at a manometric IOP of 5 mmHg, the pressure was progressively increased to 80 mmHg by raising the reservoir. At each setpoint (5, 10, 15, 20, 25, 30, 35, 40, 50, 60, 70, and 80 mmHg), triplicate telemetric measurements were taken with the EYEMATE-SC using a portable reading device for telemetric pressure transmission via a radiofrequency band. These measurements were compared to manometric pressure by linear regression analysis.

resultsA strong positive linear regression was observed between EYEMATE-SC and manometry IOPs in both canine and equine eyes (canine: R

conclusionsMeasuring canine and equine IOPs from the suprachoroidal space using the EYEMATE-SC provided accurate results over an extensive range of pressures in ex vivo globes. This telemetric sensor could assist with long-term, frequent tonometry by pet owners and clinicians following in vivo testing. Although the sensor could not detect pressures above 70 mmHg, this flaw was not considered clinically relevant.

Indexed as

Intraocular PressureTelemetryTonometry, OcularTransducers, PressureAnimalsDogsHorsesdogglaucomahorseintraocular pressure sensormanometryultrasound biomicroscopy (UBM)

Identifiers

PMID40883863
PMCPMC12488533

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.