ArticleBMC nephrology2025
Psychosocial and quality of life assessment in kidney transplant recipients: a focus on anxiety, depression, and clinical correlates.
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Identifying factors contributing to kinesiophobia in kidney transplant patients based on the fear-avoidance model: a qualitative study.Frontiers in psychology · 2026Article
- "A shared enemy to confront": the experience and needs of the partners of kidney transplant patients - a qualitative study.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- The Impact of Stress on the Functioning and Survival of Transplanted Kidneys-Biological Mechanisms, Clinical Implications, and Therapeutic Perspectives.International journal of molecular sciences · 2025Review
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7 authors.
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Abstract
backgroundKidney transplantation (KT) significantly improves survival and quality of life compared to dialysis, yet psychological disorders like anxiety and depression critically influence post-transplant outcomes.
objectivesTo evaluate the prevalence, clinical correlates, and health-related quality of life (HRQoL) impacts of anxiety and depression in Kidney transplant recipients.
methodsA cross-sectional study of 161 adult Kidney transplant recipients at a tertiary care center assessed psychosocial and clinical parameters using the Hospital Anxiety and Depression Scale (HADS) and Kidney Disease Quality of Life − 36 (KDQOL-36). Sociodemographic, clinical, and laboratory data were analyzed with multivariate regression identifying predictors.
resultsAbnormal anxiety and depression were observed in 24.3% and 9.9% of kidney transplant recipients, respectively. Anxiety correlated with elevated serum creatinine (r = 0.164, p = 0.039) and lower hemoglobin (r = -0.16, p = 0.043), while depression linked to lower hemoglobin (r = -0.172, p = 0.029) and longer transplant duration (r = 0.159, p = 0.045). Female gender, physical inactivity, psychiatric history, and higher creatinine independently predicted anxiety (all p < 0.05). Patients with abnormal anxiety or depression reported significantly poorer HRQoL, particularly in “burden of kidney disease” (65.17 ± 28.69) and mental health domains (44.85 ± 11.41).
conclusionAnxiety and depression are prevalent in Kidney transplant recipients and strongly associated with clinical markers and impaired HRQoL. Routine psychosocial screening and targeted interventions, addressing anemia, physical activity, and mental health—are essential to optimize post-transplant care. Integrating biopsychosocial models into clinical practice may enhance adherence, graft survival, and quality of life in this vulnerable population. CLINICAL TRIAL NUMBER: Not Applicable.
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