Evidence map›Paper›PMID 40883665›Full record

Trial reportBMC anesthesiology2025

Ultrasound-guided modified versus conventional serratus anterior plane block as a preemptive analgesic for unilateral video-assisted thoracoscopic surgery.

Shereen E Abd Ellatif, Asmaa M Galal Eldin, Ehab Sabry Ali, Heba M Fathi

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05661253 (Ultrasound Guided Modified Versus Conventional Serratus Anterior Plane Block as a Preemptive Analgesia for Unilateral Video-Assisted Thoracoscopic Surgery), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05661253 naunknown statusnot on this map

Ultrasound Guided Modified Versus Conventional Serratus Anterior Plane Block as a Preemptive Analgesia for Unilateral Video-Assisted Thoracoscopic Surgery

TypeinterventionalSponsorZagazig UniversityRan2022 to 2023Enrolled99ConditionsPostoperative Pain, AcuteArms25 ml of bupivacaine 0.25% via serratus anterior block, 25 ml of bupivacaine 0.25% via modified serratus anterior palne block
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Shereen E Abd EllatifDepartment of Anaesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Zagazig, Egypt. sherinelsayed@zu.edu.e.g.ORCID http://orcid.org/0000-0001-7975-2480
Asmaa M Galal EldinDepartment of Anaesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ehab Sabry AliDepartment of Cardiothoracic Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Heba M FathiDepartment of Anaesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVarious approaches to serratus anterior plane (SAP) block have been discussed in the literature. The present study aimed to compare the analgesic efficacy and postoperative pulmonary function recovery of modified serratus anterior plane block (MSAP) and conventional serratus anterior plane block (CSAP) in patients undergoing video-assisted thoracoscopic surgery (VATS).

methodsA total of 99 patients who underwent thoracoscopic surgery were randomly divided into three equal groups: a control group (C group) that received no block, a CSAP group that received preoperative conventional serratus anterior plane block, and an MSAP group that received preoperative modified serratus anterior plane block. The primary outcome was the first 24-hour tramadol consumption. The secondary outcomes were first-time-to-rescue analgesia, postoperative visual analogue score (VAS), postoperative respiratory function, and perioperative hemodynamics.

resultsThe lowest tramadol consumption and longest time to first rescue analgesia were observed in the MSAP group. The postoperative VAS score at 2, 4, and 6 h was significantly greater in the control group, but it was comparable between the two block groups. At 8 h, the VAS score was the lowest in the MSAP group. At 12, 16, and 24 h, the VAS scores were comparable among the three groups. The MSAP group presented the best respiratory function during the first postoperative 8 h. Heart rate and mean arterial blood pressure were similar in both block groups but were greater in the control group during the intraoperative period.

conclusionThe modified serratus anterior plane block is more efficient than the conventional serratus anterior plane block at reducing opioid consumption, prolonging rescue analgesic time, and improving pulmonary function recovery in patients undergoing video-assisted thoracoscopic surgery.

trial registrationThis clinical trial was approved by the Zagazig University Institutional Review Board (IRB #10060/30-10-2022), was first submitted to clinical trials.gov on 1/12/2022 and was subsequently registered retrospectively on 22/12/2022 (NCT05661253). The first research participant was enrolled on 2/12/2022.

Indexed as

Nerve BlockPostoperative PainThoracic Surgery, Video-AssistedUltrasonography, InterventionalAdultAgedAnalgesics, OpioidFemaleHumansMaleMiddle AgedPain MeasurementTramadolAnalgesics, OpioidTramadolAnalgesiaFascial plane blockRegional anaesthesiaSerratus anterior plane blockThoracic surgery.Video-assisted thoracoscopic surgery

Identifiers

PMID40883665
PMCPMC12395965

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