ArticleBMC medical imaging2025
The value of contrast-enhanced ultrasound in the follow-up of Bosniak IIF cystic renal lesions.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The "snow globe" sign: a microvascular flow imaging artifact in cystic lesions, and the role of dispersed internal debris.Abdominal radiology (New York) · 2026Article
- CEUS in Atypical Renal Cystic Masses: How, When and Why.Medicina (Kaunas, Lithuania) · 2026Review
- Imaging Assessment of Complex Renal Cysts: Comparative Value of Superb Microvascular Imaging and Contrast-Enhanced Ultrasound.Journal of personalized medicine · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContrast-enhanced ultrasound (CEUS) is increasingly used in the characterization of cystic renal lesions. Bosniak IIF lesions warrant follow-up, and their reported progression rate remains variable.
methodsIn this single-center retrospective study we assessed renal CEUS exams (SonoVue
resultsSignificant (p = 0.037) positive correlation was found between patient age and lesion size. 33.9% of patients were immediately lost to follow-up, and they tended to be younger, albeit not significantly (p = 0.09). Recommendation for follow-up imaging was indicated in 66.1% of the initial radiological reports. Follow-up adherence was not significantly lower for lesions with absent recommendation (55% vs. 70.27%, p = 0.26). Fewer (52%) female vs. male (74.19%) patients had a follow-up recommendation (p = 0.1, not significant). 10.8% of the followed lesions demonstrated progression within 5 years. Lesion reevaluation according to the 2020 European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) criteria resulted in 77.36% agreement with 22.2% of lesions being downgraded, and a single lesion being upgraded (p = 0.0015, significant).
conclusionsFollow-up adherence of Bosniak IIF cystic renal lesions was found to be suboptimal, with potential gender disparities. Standardization of follow-up recommendation in the report is an unmet need. Progression rate remains low, but is expected to change with the adoption of novel CEUS-specific criteria. The EFSUMB criteria in particular can improve selection of truly indeterminate lesions.
trial registrationRetrospectively registered.
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