Evidence map›Paper›PMID 40883645›Full record

ArticleEuropean radiology experimental2025

Photon-counting CT versus energy-integrating detector and flat-panel CT for cadaveric wrist arthrography with additional tin filter dose reduction.

Johannes de Boer, Nigar Salimova, Friederike Weidemann, Lea Behrendt, Thomas Werncke, Frank K Wacker, Lena Sonnow

Abstract readComparative Study
In one paragraph

Article in European radiology experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johannes de BoerDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany. johannes.dbh@gmail.com.ORCID http://orcid.org/0009-0001-7658-4618
Nigar SalimovaDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Friederike WeidemannDepartment of Trauma Surgery, Hannover Medical School, Hannover, Germany.
Lea BehrendtDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Thomas WernckeDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Frank K WackerDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Lena SonnowDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the imaging performance and diagnostic value of a photon-counting detector (PCD) computed tomography (CT) compared to an energy-integrating detector (EID) and flat panel detector (FPD) for cadaveric wrist arthrographies.

methodsFollowing ethics committee approval, ten cadaveric wrists were injected with diluted iodinated contrast agent. CT arthrographies using PCD-, EID-, and FPD-CT were performed. Six dose protocols between 0.1 mGy (using a tin filter) and 6 mGy, ultrahigh-resolution-mode, and two reconstruction kernels were used for the PCD-CT and EID-CT. FPD-CT images were reconstructed using a "normal" and "sharp" kernel. Signal-to-noise ratios (SNR) and contrast-to-noise ratios (CNR) were calculated and analyzed using analysis of variance (ANOVA) and post hoc tests. Three blinded radiologists independently rated image quality concerning trabecular, cartilage, and intrinsic structures. Intraclass correlation coefficients (ICC) were calculated, followed by a Friedman and post hoc test.

resultsAt 1.5 mGy, 3 mGy, and 6 mGy with the Br89 kernel, the PCD-CT yielded up to 2.35 times higher SNR and up to 7 times higher CNR than dose-equivalent and higher dose EID-CT scans. Subjective ratings favored the PCD-CT over the EID-CT and occasionally the FPD-CT, with a combined ICC of 0.942. Applying sharper kernels, SNR did not differ significantly between the PCD-CT (1.5 mGy, 3 mGy, and 6 mGy) and the FPD-CT.

conclusionUsing sharp kernels, the PCD-CT provided superior image quality to the EID-CT and achieved comparable or better quality than the FPD at certain parameters. Thus, the PCD-CT could be considered a possible alternative in clinical routine for evaluating wrist injuries. RELEVANCE STATEMENT: This study demonstrates the potential of the PCD-CT as a valuable tool in diagnosing wrist injuries. Its superior image quality compared to the EID-CT can increase confidence in diagnosing subtle bone pathologies and additionally yields the possibility of radiation exposure reduction. KEY POINTS: The technical advantages of the PCD-CT allow for dose reduction while generating high-quality images. PCD-CT showed superior image quality over EID-CT and was comparable to the FPD-CT. PDC-CT offers improved visualization of fine joint structures in wrist arthrography and should be considered in clinical routine.

Indexed as

ArthrographyTomography, X-Ray ComputedWrist JointCadaverContrast MediaHumansPhotonsRadiation DosageSignal-To-Noise RatioTinWristContrast MediaTinArthrographyCadaverMusculoskeletal systemTomography (x-ray computed)Wrist joint

Identifiers

PMID40883645
PMCPMC12397008

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.